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Cartoon of scientist deciding whether to go down the path of well-studied genes or that of the neglected genes.
Stepping Into the Unknome
A database of neglected genes may help unlock the mysteries hiding in the overlooked regions of the proteome.
Stepping Into the Unknome
Stepping Into the Unknome

A database of neglected genes may help unlock the mysteries hiding in the overlooked regions of the proteome.

A database of neglected genes may help unlock the mysteries hiding in the overlooked regions of the proteome.

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Notch

A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
Short, Strong Signals
Ruth Williams | Mar 25, 2015 | 3 min read
Methylation increases both the activity and instability of the signaling protein Notch.
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