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Immunotherapy More Effective in Men: Study
Kerry Grens | May 18, 2018
Women with metastatic cancer who were treated with a checkpoint inhibitor had a smaller benefit than did men.
Mitochondrial DNA Plays a Role in Metastasis
Kerry Grens | Apr 18, 2018
Experiments in mice show that mitochondria, both within the tumor and beyond, can make the difference between promoting or inhibiting cancer spread.
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Kerry Grens | Apr 16, 2018
Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.
Cancer Evolutionist: A Profile of Charles Swanton
Anna Azvolinsky | Mar 31, 2018
Motivated by his father’s cancer diagnosis, the Francis Crick Institute cancer geneticist has been revealing the ways tumors evolve and why they are so difficult to treat.
Transgenic Mouse Illuminates Melanoma Metastasis
Abby Olena | Jun 28, 2017
Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels.
Cancer Studies Seem Replicable
Kerry Grens | Jun 27, 2017
In the latest findings from the Reproducibility Project: Cancer Biology, independent researchers achieve results that mirror those of two earlier papers.
Immune Cells Deliver Cancer Drugs to the Brain
Diana Kwon | Jun 19, 2017
Neutrophils loaded with the chemotherapy drug paclitaxel traverse the blood-brain barrier and kill residual cancer cells after tumor-resection surgery in mice.
Trump Picks National Cancer Institute Director
Kerry Grens | Jun 12, 2017
Ned Sharpless currently leads the cancer center at the University of North Carolina, Chapel Hill.
Rare T Cells Fight Cancer
Jef Akst | Apr 30, 2017
A new approach to immunotherapy finds that the immune-cell clonotypes that come to the rescue start out at very low frequencies.
A History of Screening for Natural Products to Fight Cancer
Jef Akst | Mar 31, 2017
In the middle of the 20th century, the National Cancer Institute began testing plant extracts for chemotherapeutic potential—helping to discover some drugs still in use today.