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Cancers Protect Themselves Against Their Own Mutations
Cancers Protect Themselves Against Their Own Mutations
Tumors overexpress certain genes to survive a growing pile of harmful mutations, a trait that scientists could exploit to target with drugs.
Tumors overexpress certain genes to survive a growing pile of harmful mutations, a trait that scientists could exploit to target with drugs.
oncology
Helping Engineered T Cells Find Their Way to Tumors
Nele Haelterman, PhD | Apr 18, 2023 | 3 min read
Susan Thomas discusses how her team engineered a microfluidic device to screen for T cells with improved homing capability to tumor cells.
![jigsaw puzzle with magnifying glass over the word "metastasis" ](https://cdn.the-scientist.com/assets/articleNo/70540/aImg/47882/49929-800x5607-t.jpg "jigsaw puzzle with magnifying glass over the word "metastasis" ")
Breast Cancer Cells Retrain T Cells to Invade Specific Tissues
Nele Haelterman, PhD | Sep 26, 2022 | 3 min read
Scientists discover tumor-associated T cells that drive breast cancer metastasis to lymph nodes.
How to Speed Up Cell Therapy Development Processes
The Scientist’s Creative Services Team | 1 min read
In this webinar, Patrick Schmidt will explore how to streamline CAR T cell product manufacturing processes for immunotherapy.
White House Names Monica Bertagnolli as NCI Director
Andy Carstens | Aug 10, 2022 | 2 min read
The announcement confirms earlier reports that Bertagnolli will become the first woman to lead the National Cancer Institute since its founding in 1937.
Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments
Ryan Layer, The Conversation | May 27, 2022 | 5 min read
Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.
Understanding How Single Cell Evolution Drives Tumor Complexity
The Scientist’s Creative Services Team | 1 min read
Andris Abramenkovs and Mark Lynch will discuss how to overcome challenges obtaining high-definition genomic data from single cells.
Tool Would Use Tumor Gene Expression to Inform Radiation Dose
Alejandra Manjarrez, PhD | Aug 27, 2021 | 4 min read
In a retrospective analysis, a team found that an algorithm integrating the gene expression of a tumor with the radiation dose a patient received predicted how well the patient responded to the treatment.
Microscopic Robots Deliver Drugs to the Brain
Asher Jones | Mar 30, 2021 | 5 min read
Researchers turned white blood cells called neutrophils into drug-smuggling “neutrobots,” which penetrated the blood-brain barrier to treat brain cancer in mice.
A Guide to Mapping the Complexity of the Tumor Microenvironment
The Scientist’s Creative Services Team | 1 min read
High-quality sample preparation, single-cell analysis, and ultra-high content spatial proteomics for multi-dimensional research workflows.
José Baselga, Renowned Oncologist, Dies at 61
Asher Jones | Mar 22, 2021 | 2 min read
The cancer researcher and executive vice president of AstraZeneca’s oncology research and development is well known for his role in the development of pivotal breast cancer therapies.
Pioneering Cancer Researcher Emil Freireich Dies at 93
Asher Jones | Feb 5, 2021 | 3 min read
The oncologist developed lifesaving childhood leukemia treatments and revolutionized chemotherapy.
Bringing Fluency to Clinical Diagnostics Through Automation
Tecan | 1 min read
Automated liquid handling workstations offer flexibility for a wide range of application and process needs.
Scientists Discover New Human Salivary Glands
Diana Kwon | Oct 21, 2020 | 4 min read
The findings may have implications for radiotherapy, a cancer treatment that can cause damage to salivary glands and leave lasting complications.
Heart Attack Elevates Risk of Breast Cancer Recurrence: Study
Amanda Heidt | Jul 13, 2020 | 4 min read
Mice that experienced heart attacks underwent a large-scale shift in their immune systems that allowed cancer to flourish, perhaps explaining the observation in patients.
Realizing the Potential of Spatial Biology for a Noncanonical Model
The Scientist’s Creative Services Team | 1 min read
In this webinar, Shaye Hagler will discuss the unexplored capabilities of ChipCytometryTM Spatial Multiplexing Technology for advancing spatial biology research.
Paul Marks, Past President of MSKCC, Dies
Catherine Offord | May 8, 2020 | 3 min read
A cancer researcher with a talent for leadership, Marks turned the Memorial Sloan Kettering Cancer Center into one of the world’s foremost oncology research institutions.
Who Benefits from Herceptin and Other Anti-HER2 Cancer Therapies?
Robert Fortner | Apr 12, 2020 | 7 min read
Calls to include a new breast cancer subtype in future clinical trials reveal fundamental disagreements about HER2’s role in the disease.
Developing Effective Cell Therapies for Challenging Cancer Types
The Scientist’s Creative Services Team | 1 min read
In this webinar, Sandhya Sharma will discuss how to enrich for antigen-specific T-cells to treat virus-associated malignancies.
Biochemist Stanley Cohen Dies
Catherine Offord | Feb 10, 2020 | 2 min read
The Vanderbilt University professor was awarded a Nobel Prize for his discovery of epidermal growth factor.