Found: A Cancer Drug’s Mechanism of Action
Found: A Cancer Drug’s Mechanism of Action
As ONC201 moves through human clinical trials, scientists finally figure out that the compound and its analogs target a mitochondrial protease.
Found: A Cancer Drug’s Mechanism of Action
Found: A Cancer Drug’s Mechanism of Action

As ONC201 moves through human clinical trials, scientists finally figure out that the compound and its analogs target a mitochondrial protease.

As ONC201 moves through human clinical trials, scientists finally figure out that the compound and its analogs target a mitochondrial protease.

oncology
Cancer Leader LaSalle Leffall, Jr. Dies
Cancer Leader LaSalle Leffall, Jr. Dies
Ashley Yeager | May 30, 2019
The Howard University surgeon was the first African American president of the American Cancer Society and mentored thousands of medical students.
AI Uses Images and Omics to Decode Cancer
AI Uses Images and Omics to Decode Cancer
Amber Dance | May 1, 2019
Machine learning can analyze photographs of cancer, tumor pathology slides, and genomes. Now, scientists are poised to integrate that information into cancer uber-models.
A Revised CAR T for Lymphoma Has Fewer Side Effects
A Revised CAR T for Lymphoma Has Fewer Side Effects
Kerry Grens | Apr 23, 2019
An early-stage clinical study finds that none of the 25 patients treated developed neurotoxicity or cytokine release syndrome, common hazards of the cancer immunotherapy.
Q&A: Epigenetic Therapies for Breast Cancer
Q&A: Epigenetic Therapies for Breast Cancer
Katarina Zimmer | Apr 4, 2019
Breast cancer researcher and oncologist Nancy Davidson discusses what we’ve learned from the first wave of epigenetic trials for breast cancer, and what challenges lie ahead before such therapies reach the clinic.
Contending with Resistance in Cancer Immunotherapy
Contending with Resistance in Cancer Immunotherapy
Marissa Fessenden | Apr 1, 2019
Researchers describe ways to study how cancer cells evade therapies that harness the immune system.
Cancer-Specific Antigens Encoded in “Junk” DNA
Cancer-Specific Antigens Encoded in “Junk” DNA
Carolyn Wilke | Apr 1, 2019
Researchers found that allegedly noncoding genetic material carries the instructions for many peptides that may help harness the immune system to fight cancer.
Past President of the AACR, Waun Ki Hong, Dies
Past President of the AACR, Waun Ki Hong, Dies
Carolyn Wilke | Jan 7, 2019
The former head of cancer medicine at MD Anderson Cancer Center helped change clinical practice for laryngeal cancer and helped establish chemoprevention.
Bristol-Myers Squibb to Buy Celgene for $74 Billion
Bristol-Myers Squibb to Buy Celgene for $74 Billion
Catherine Offord | Jan 3, 2019
The deal between the two biopharmaceutical giants will boost the purchaser’s cancer drug portfolio.
GlaxoSmithKline to Acquire Cancer Biotech TESARO for $5.1 Billion
GlaxoSmithKline to Acquire Cancer Biotech TESARO for $5.1 Billion
Carolyn Wilke | Dec 3, 2018
The purchase aims to build GSK’s oncology pipeline.