Genome, Exome, RNA Sequencing Applied to Pediatric Cancer Cases
Genome, Exome, RNA Sequencing Applied to Pediatric Cancer Cases
Combining data from the genetic testing techniques can guide patient care, scientists say.
Genome, Exome, RNA Sequencing Applied to Pediatric Cancer Cases
Genome, Exome, RNA Sequencing Applied to Pediatric Cancer Cases

Combining data from the genetic testing techniques can guide patient care, scientists say.

Combining data from the genetic testing techniques can guide patient care, scientists say.

oncology
New Insights to Improve CAR T Cells’ Safety
New Insights to Improve CAR T Cells’ Safety
Vicki Brower | Jun 5, 2018
Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.
A T-Cell Tweak Combats Advanced Breast Cancer
A T-Cell Tweak Combats Advanced Breast Cancer
Ashley Yeager | Jun 5, 2018
The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.
Immunotherapy More Effective in Men: Study
Immunotherapy More Effective in Men: Study
Kerry Grens | May 18, 2018
Women with metastatic cancer who were treated with a checkpoint inhibitor had a smaller benefit than did men.
Mitochondrial DNA Plays a Role in Metastasis
Mitochondrial DNA Plays a Role in Metastasis
Kerry Grens | Apr 18, 2018
Experiments in mice show that mitochondria, both within the tumor and beyond, can make the difference between promoting or inhibiting cancer spread.
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Kerry Grens | Apr 16, 2018
Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  
Cancer Evolutionist: A Profile of Charles Swanton
Cancer Evolutionist: A Profile of Charles Swanton
Anna Azvolinsky | Apr 1, 2018
Motivated by his father’s cancer diagnosis, the Francis Crick Institute cancer geneticist has been revealing the ways tumors evolve and why they are so difficult to treat.
Transgenic Mouse Illuminates Melanoma Metastasis
Transgenic Mouse Illuminates Melanoma Metastasis
Abby Olena | Jun 28, 2017
Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels. 
Cancer Studies Seem Replicable
Cancer Studies Seem Replicable
Kerry Grens | Jun 27, 2017
In the latest findings from the Reproducibility Project: Cancer Biology, independent researchers achieve results that mirror those of two earlier papers.
Immune Cells Deliver Cancer Drugs to the Brain
Immune Cells Deliver Cancer Drugs to the Brain
Diana Kwon | Jun 19, 2017
Neutrophils loaded with the chemotherapy drug paclitaxel traverse the blood-brain barrier and kill residual cancer cells after tumor-resection surgery in mice.