Immunotherapy Combo Reduces Solid Tumors in Mice
Immunotherapy Combo Reduces Solid Tumors in Mice
When tumor cells are infected with an oncolytic virus carrying a modified CD19 gene, they become targets for CAR T cells engineered to recognize this molecular marker.
When tumor cells are infected with an oncolytic virus carrying a modified CD19 gene, they become targets for CAR T cells engineered to recognize this molecular marker.
oncolytic viruses
Death by Stem Cell: Developing New Cancer Therapies
Charlene Lancaster, PhD | Jul 24, 2023 | 3 min read
Khalid Shah engineers stem cells to deliver cancer therapeutics directly to tumors, thereby increasing their efficacy.
Zika as Cancer Buster?
Amy Schleunes | Apr 1, 2020 | 2 min read
By infecting glioblastoma cells but not healthy brain tissue, some form of the virus could serve a therapeutic purpose.
Five Oncoviruses Debut On NIH Carcinogen List
Joshua A. Krisch | Nov 6, 2016 | 2 min read
Seven newly evaluated substances, including five oncoviruses, have been added to the US National Institutes of Health’s 14th Report on Carcinogens.
FDA OKs Herpesvirus to Treat Cancer
Jef Akst | Oct 28, 2015 | 1 min read
The US Food and Drug Administration’s approval of an engineered herpesvirus for the treatment of melanoma marks the first oncolytic virus to enter the market.
Yvonne Saenger: Immunotherapy Pioneer
Jef Akst | Apr 1, 2015 | 3 min read
Assistant Professor, Department of Medicine, Columbia University. Age: 41
Cancer Immunotherapist
Jef Akst | Mar 31, 2015 | 1 min read
Scientist to Watch Yvonne Saenger explains recent advances in using biomarkers to identify cancer patients who might benefit most from immunotherapy.
Speaking of Science
The Scientist | Dec 1, 2014 | 2 min read
December 2014's selection of notable quotes
Contributors
Rina Shaikh-Lesko | Jun 1, 2014 | 3 min read
Meet some of the people featured in the June 2014 issue of The Scientist
Tactical Maneuvers
Stephanie Swift | Jun 1, 2014 | 10+ min read
Scientists are creating viruses that naturally home in on tumor cells while simultaneously boosting the body’s immune system to fight cancer.
Targeting Tumors with Viruses
Stephanie Swift | May 31, 2014 | 1 min read
Stephanie Swift discusses the strategy of fighting cancer with viruses.
Cancer-Fighting Virus
Ruth Williams | Jun 13, 2012 | 3 min read
A small patient trial offers hope that cancer-killing viruses might be a viable therapy after all.