Morphine Tolerance Pathway Identified in Mice
Morphine Tolerance Pathway Identified in Mice
Prolonged exposure to morphine triggers cells in the spine to release signaling molecules that increase pain sensitivity and dull the relief of the drug. Blocking this activity could improve pain management.
Morphine Tolerance Pathway Identified in Mice
Morphine Tolerance Pathway Identified in Mice

Prolonged exposure to morphine triggers cells in the spine to release signaling molecules that increase pain sensitivity and dull the relief of the drug. Blocking this activity could improve pain management.

Prolonged exposure to morphine triggers cells in the spine to release signaling molecules that increase pain sensitivity and dull the relief of the drug. Blocking this activity could improve pain management.

painkillers
Neuron-Released Protein Can Set Off Inflammation: Study
Neuron-Released Protein Can Set Off Inflammation: Study
Marcus A. Banks | Aug 19, 2021
Research in mice suggests that moderating nerve activity with drugs or electrical pulses could modify tissue immune responses, curtailing the chronic pain often associated with inflammatory conditions.
Ibuprofen’s Effects Found in Offspring of Exposed Mosquitoes
Ibuprofen’s Effects Found in Offspring of Exposed Mosquitoes
Carolyn Wilke | Oct 1, 2018
Results of a study suggest that toxicologists should look further than exposed individuals for contaminant effects.
Synthetic Botox Treats Chronic Pain in Mice
Synthetic Botox Treats Chronic Pain in Mice
Abby Olena | Jul 18, 2018
Researchers silence pain neurons in the mouse spinal cord with injections of botulinum toxins modified to bind to the neurons’ receptors.
NIH Won’t Use Industry Money for Opioid Research Initiative
NIH Won’t Use Industry Money for Opioid Research Initiative
Shawna Williams | Apr 19, 2018
The announcement comes after an agency working group recommends against an industry partnership on ethical grounds.
Sex Differences in Opioid Analgesia: A Complicated Picture
Sex Differences in Opioid Analgesia: A Complicated Picture
Catherine Offord | Jan 1, 2018
Researchers are beginning to tease apart the mechanisms underlying differences in how males and females respond to powerful painkillers.
Prospecting for Painkillers
Prospecting for Painkillers
The Scientist Staff | Dec 31, 2017
Cone snail venom researcher Mandë Holford discusses the therapeutic potential of toxins found in animals.
CDC Offers Advice to Limit Opioid Scripts
CDC Offers Advice to Limit Opioid Scripts
Kerry Grens | Mar 17, 2016
Aimed at primary care providers, the recommendations encourage non-narcotic alternatives or short-term opioid prescriptions and patient monitoring.
FDA OKs Overdose Treatment Device
FDA OKs Overdose Treatment Device
Rina Shaikh-Lesko | Apr 4, 2014
The U.S. Food and Drug Administration approves a long-awaited handheld device for the treatment of opioid-overdose emergencies.
An Offensive Playbook
An Offensive Playbook
Mary Beth Aberlin | Feb 1, 2014
Developing nonaddictive drugs to combat pain