Oleh Hornykiewicz, Who Pioneered Treatment for Parkinson’s, Dies
Oleh Hornykiewicz, Who Pioneered Treatment for Parkinson’s, Dies
The University of Toronto and University of Vienna pharmacologist developed L-dopa, a precursor to dopamine that remains the most widely used therapy for Parkinson’s disease.
Oleh Hornykiewicz, Who Pioneered Treatment for Parkinson’s, Dies
Oleh Hornykiewicz, Who Pioneered Treatment for Parkinson’s, Dies

The University of Toronto and University of Vienna pharmacologist developed L-dopa, a precursor to dopamine that remains the most widely used therapy for Parkinson’s disease.

The University of Toronto and University of Vienna pharmacologist developed L-dopa, a precursor to dopamine that remains the most widely used therapy for Parkinson’s disease.

Parkinson's
Into the Light: A Profile of Joanne Chory
Into the Light: A Profile of Joanne Chory
Emily Makowski | Mar 1, 2020
The plant geneticist has revolutionized researchers’ understanding of how light affects plant growth and development, and is engineering plants to combat climate change.
Neural Stem Cell Transplantation Crawls Toward the Clinic
Neural Stem Cell Transplantation Crawls Toward the Clinic
Ashley P. Taylor | Oct 29, 2019
Several early-stage clinical trials indicate that implanting patients with the cells is safe. But whether they can alleviate neurological problems remains to be seen.
Is It Time to Rethink Parkinson’s Pathology?
Is It Time to Rethink Parkinson’s Pathology?
Ashley Yeager | Oct 1, 2019
New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Ashley Yeager | Oct 1, 2019
Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.
Mouse Model Shows How Parkinson’s Disease Begins in the Gut
Mouse Model Shows How Parkinson’s Disease Begins in the Gut
Emma Yasinski | Jun 26, 2019
Johns Hopkins’s Ted Dawson discusses his lab’s demonstration that misfolded α-synuclein can move from the stomach to the brain and cause physical and cognitive symptoms.
Chemicals on the Skin Could Enable Parkinson’s Detection
Chemicals on the Skin Could Enable Parkinson’s Detection
Shawna Williams | Mar 20, 2019
Researchers teamed up with a woman with a keen sense of smell to identify telling differences between healthy people and those with the neurodegenerative disease.
Increasing Number of iPS Cell Therapies Tested in Clinical Trials
Increasing Number of iPS Cell Therapies Tested in Clinical Trials
Katarina Zimmer | Nov 28, 2018
Since their discovery in 2006, induced pluripotent stem cells have been poised to reprogram regenerative medicine. Twelve years on, here’s how far they’ve come.
Randy Schekman to Leave <em>eLife</em>
Randy Schekman to Leave eLife
Kerry Grens | Aug 19, 2018
The founding editor-in-chief will redirect his focus to a Parkinson’s organization.
Trial Launched to Treat Parkinson&rsquo;s with Reprogrammed Stem Cells
Trial Launched to Treat Parkinson’s with Reprogrammed Stem Cells
Diana Kwon | Jul 31, 2018
Surgeons will inject approximately 5 million dopamine-producing progenitor cells into patients’ brains.
Copper Connections
Copper Connections
Jim Daley | May 1, 2018
Researchers initially set out to investigate the relationship between copper homeostasis and the rare Menkes disease, but they also found links to Parkinson’s.
World’s First Commercial iPSC Cell Plant Opens in Japan
World’s First Commercial iPSC Cell Plant Opens in Japan
Jim Daley | Mar 23, 2018
The $340 million, 30,000-square-foot center will produce cells for therapeutic applications.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
DBS with Nanoparticle-Based Optogenetics Modifies Behavior in Mice
DBS with Nanoparticle-Based Optogenetics Modifies Behavior in Mice
Diana Kwon | Feb 8, 2018
Researchers develop a new technique to selectively activate neurons deep in the rodent brain, taking a step toward noninvasive brain stimulation for neurological disorders.
Cellular Senescence in Astrocytes May Play Central Role in Parkinson’s Disease
Cellular Senescence in Astrocytes May Play Central Role in Parkinson’s Disease
Katarina Zimmer | Jan 24, 2018
The elimination of these glia in the mouse brain ameliorated the development of Parkinsonian neuropathologies induced by the pesticide toxin paraquat.  
Research Links Gut Health to Neurodegeneration
Research Links Gut Health to Neurodegeneration
Jef Akst | Nov 13, 2017
Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.
Parkinson’s Disease Cell Therapy Relieves Symptoms in Monkeys
Parkinson’s Disease Cell Therapy Relieves Symptoms in Monkeys
Abby Olena | Aug 30, 2017
Neurons derived from human induced pluripotent stem cells fill in for lost dopamine neurons in a primate model of the disease.
The Regenerator
The Regenerator
Anna Azvolinsky | Dec 1, 2015
In his search for effective therapies for Parkinson’s disease, Lorenz Studer is uncovering pluripotency switches and clues to what makes cells age.
New Hope for Alzheimer’s Blood Test
New Hope for Alzheimer’s Blood Test
Jef Akst | Oct 19, 2015
Using autoantibodies as biomarkers, researchers could soon identify people at the highest risk of developing neurodegenerative diseases much earlier than existing methods.