Overcoming Roadblocks in PROTAC Characterizations
Overcoming Roadblocks in PROTAC Characterizations
Researchers require an accurate and high throughput method to evaluate proteolysis targeting chimera (PROTAC) interactions.
Researchers require an accurate and high throughput method to evaluate proteolysis targeting chimera (PROTAC) interactions.
protein-ligand interactions
A Quick and Efficient Strategy for Affinity Screening
NanoTemper Technologies | Dec 7, 2023 | 1 min read
Researchers assessed the binding affinities of PROTAC binary and ternary complexes with Spectral Shift technology.
A Solution for Measuring In-Solution Interactions
NanoTemper Technologies | Dec 5, 2023 | 1 min read
Scientists used Spectral Shift assays to assess binding affinity and degradation of the oncogene regulator WDR5.
Boosting Throughput with a Label-Free Kinetic Assay
Malvern Panalytical | Jul 31, 2023 | 1 min read
The revolutionary waveRAPID® technique enables biological breakthroughs and improves high throughput drug discovery.
A Bright New Tool to Record Cellular Interactions
Lisa Winter | Apr 1, 2021 | 3 min read
The G-baToN prototype transfers GFP between cells, illuminating cell-cell contacts.
Cracking the Complex
Jeffrey M. Perkel | Nov 1, 2015 | 8 min read
Using mass spec to study protein-protein interactions
Screening Goes In Silico
Carina Storrs | Feb 1, 2015 | 8 min read
Computational tools take some of the cost—and guesswork—out of drug discovery.