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An illustration of a protein ribbon resting on a glossy surface.
The Journey to a Nobel Prize: A Protein Design and Structure Research Timeline
About 50 years ago, biologists set out to solve the protein-folding problem. The road to the Nobel victory has been arduous but full of small wins along the way.
The Journey to a Nobel Prize: A Protein Design and Structure Research Timeline
The Journey to a Nobel Prize: A Protein Design and Structure Research Timeline

About 50 years ago, biologists set out to solve the protein-folding problem. The road to the Nobel victory has been arduous but full of small wins along the way.

About 50 years ago, biologists set out to solve the protein-folding problem. The road to the Nobel victory has been arduous but full of small wins along the way.

protein structure

A Comprehensive Guide to Proteomics
What Is Proteomics?
Sejal Davla, PhD | Dec 9, 2024 | 7 min read
Explore proteomics concepts, approaches, and data analysis.
Black and gold sketch of David Baker, Demis Hassabis, and John Jumper.<strong >&nbsp;</strong>
Nobel Prize in Chemistry for Work on Proteins
Sneha Khedkar | Oct 9, 2024 | 3 min read
David Baker, Demis Hassabis, and John Jumper share this year’s Chemistry award for their research on protein design and structure prediction.
Collection of green and blue proteins with different conformations on a black background.
The Dynamic Lives of Intrinsically Disordered Proteins
Danielle Gerhard, PhD | Sep 13, 2024 | 10+ min read
Shapeshifting proteins challenge a long-standing maxim in biology.
Infographic depicting the variety of conformations that proteins can assume and how this facilitates multifunctionality.
Infographic: Shapeshifters in the Proteome
Danielle Gerhard, PhD | Sep 13, 2024 | 2 min read
Textbooks often depict proteins as nicely folded three-dimensional structures, but many proteins are far from it.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Technique Talk: The Fundamentals of Mass Spectrometry-Based Proteomics
Technique Talk: The Fundamentals of Mass Spectrometry-Based Proteomics
The Scientist | May 23, 2023 | 1 min read
Learn the basics of proteomics analysis and nanoLC-MS/MS data acquisition.
Artist&rsquo;s rendition of translucent teal proteins comprised of red spherical amino acids
Now AI Can Be Used to Design New Proteins
Kamal Nahas, PhD | Mar 3, 2023 | 4 min read
Machine learning can be harnessed to synthesize artificial light-bearing enzymes that actually work in cells.
Tree with many scattered branches.
Scientists Resurrect Ancient Rubiscos to Understand Their Evolution
Alejandra Manjarrez, PhD | Oct 14, 2022 | 5 min read
A team proposes that the addition of a small accessory subunit to the carbon-fixing enzyme was key to improving its catalytic properties and specificity to CO2.
A ball-and-stick plus ribbons molecular model of the hormone orexin, also known as hypocretin, isolated on a white background.
2023 Breakthrough Prizes Showcase Research in AI and Narcolepsy
Amanda Heidt | Sep 22, 2022 | 2 min read
Three prizes were awarded to six researchers working across the life sciences on cellular organization, protein structure, and the genetic underpinnings of a chronic sleep disorder.
Infographic about SLiMs in SARS-CoV-2 Infection
Infographic: Short Protein Motifs’ Role in SARS-CoV-2 Infection
Conchita Fraguas Bringas and Jakob Nilsson | May 16, 2022 | 4 min read
Known as SLiMs, these stretches of up to 10 amino acids play notable roles in cell biology, including responses to viral invasion.
Multiplexed and Trackable CRISPR-Based Genome Engineering
A Platform for Automated CRISPR-Based Microbial Genome Engineering
Inscripta | Jan 25, 2022 | 1 min read
Discover how you can design and generate genomic edits to optimize heterologous protein expression and activity in E. coli.
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Probing Antibody Binding to the SARS-CoV-2 Spike Protein
The Scientist Creative Services Team in collaboration with Refeyn | Oct 29, 2021 | 2 min read
Victor Yin will discuss two single-particle mass analysis methods that shed light on heterogenous, multimeric proteins and their interactions.
Understanding Cancer Using Cryo-EM
Understanding the Complexity of Cancer with Cryo-EM
The Scientist and Thermo Fisher Scientific | Oct 12, 2021 | 1 min read
Explore how researchers use cryogenic electron microscopy (cryo-EM) to identify how mutations affect protein signaling and function through structural or conformational changes.
Learn How to Accurately Determine Protein Conformation
Focus on Structure to Verify Protein Function
The Scientist and RedShift Bio | Oct 6, 2021 | 1 min read
Scientists analyze a therapeutic protein’s secondary structure to confirm drug efficacy and safety.
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Using Nanopores to Sense and Sequence Proteins
The Scientist | Aug 30, 2021 | 1 min read
Aleksei Aksimentiev and Stefan Howorka discuss challenges in amino acid sensing with nanopores and approaches to design efficient protein sequencing technology.
Detect Protein Structural Changes with MMS
A More Sensitive Way to Determine Protein Structure
RedShift Bio | Aug 16, 2021 | 1 min read
Reliable protein stability and similarity measurements using microfluidic modulation spectroscopy
Scientific Breakthroughs with Cryogenic Electron Microscopy
The Scientist and Thermo Fisher Scientific | Jun 10, 2021 | 1 min read
Structures made via cryo-EM give researchers insights into SARS-CoV-2, HIV, neurological disorders, cancer, and more.
Transforming Virology Research with Cryo-EM
The Scientist and Thermo Fisher Scientific | May 11, 2021 | 1 min read
Explore what researchers can do with Cryo-EM
Accelerating Discovery in the Age of a Pandemic
The Scientist | Jan 22, 2021 | 2 min read
An expert panel will present how synthetic biology accelerates the development of diagnostics, therapeutics, and the medicinal pipeline.
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