protein structure

Explore proteomics concepts, approaches, and data analysis.

David Baker, Demis Hassabis, and John Jumper share this year’s Chemistry award for their research on protein design and structure prediction.

Shapeshifting proteins challenge a long-standing maxim in biology.

Textbooks often depict proteins as nicely folded three-dimensional structures, but many proteins are far from it.

p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.

Learn the basics of proteomics analysis and nanoLC-MS/MS data acquisition.

Machine learning can be harnessed to synthesize artificial light-bearing enzymes that actually work in cells.

A team proposes that the addition of a small accessory subunit to the carbon-fixing enzyme was key to improving its catalytic properties and specificity to CO₂.

Three prizes were awarded to six researchers working across the life sciences on cellular organization, protein structure, and the genetic underpinnings of a chronic sleep disorder.

Known as SLiMs, these stretches of up to 10 amino acids play notable roles in cell biology, including responses to viral invasion.

Discover how you can design and generate genomic edits to optimize heterologous protein expression and activity in E. coli.

Victor Yin will discuss two single-particle mass analysis methods that shed light on heterogenous, multimeric proteins and their interactions.

Explore how researchers use cryogenic electron microscopy (cryo-EM) to identify how mutations affect protein signaling and function through structural or conformational changes.

Scientists analyze a therapeutic protein’s secondary structure to confirm drug efficacy and safety.

Aleksei Aksimentiev and Stefan Howorka discuss challenges in amino acid sensing with nanopores and approaches to design efficient protein sequencing technology.

Reliable protein stability and similarity measurements using microfluidic modulation spectroscopy

Structures made via cryo-EM give researchers insights into SARS-CoV-2, HIV, neurological disorders, cancer, and more.

Explore what researchers can do with Cryo-EM

An expert panel will present how synthetic biology accelerates the development of diagnostics, therapeutics, and the medicinal pipeline.