Spike Structure Gives Insight into SARS-CoV-2 Evolution
Spike Structure Gives Insight into SARS-CoV-2 Evolution
Researchers demonstrate that the SARS-CoV-2 spike protein is more stable and binds the human ACE2 receptor with much higher affinity than the spike protein of its closest known relative, bat coronavirus RaTG13.
Spike Structure Gives Insight into SARS-CoV-2 Evolution
Spike Structure Gives Insight into SARS-CoV-2 Evolution

Researchers demonstrate that the SARS-CoV-2 spike protein is more stable and binds the human ACE2 receptor with much higher affinity than the spike protein of its closest known relative, bat coronavirus RaTG13.

Researchers demonstrate that the SARS-CoV-2 spike protein is more stable and binds the human ACE2 receptor with much higher affinity than the spike protein of its closest known relative, bat coronavirus RaTG13.

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Crowdsourced Protein Simulation Exceeds Supercomputers’ Power
Shawna Williams | Apr 15, 2020
Folding@Home, currently focused on deciphering the workings of SARS-CoV-2, is the first project to have exascale-level computational muscle.
Nobel-Winning Biochemist Paul Boyer Dies
Shawna Williams | Jun 7, 2018
The UCLA researcher was lauded for figuring out how ATP synthase works.
Unknown Protein Structures Predicted
Ruth Williams | Jan 19, 2017
Metagenomic sequence data boosts the power of protein modeling software to yield hundreds of new protein structure predictions.
Video: Inner Circle
The Scientist Staff | Nov 30, 2016
See an animation that illustrates emerging insights into the inner ring structures of the nuclear pore complex.
Fraudulent Paper Pulled
Bob Grant | Jan 5, 2016
Nature retracts a study six years after an investigation found that the protein structures it reported were fabricated.
Getting Back in Shape
Karen Zusi | Dec 1, 2015
Contrary to years of research suggesting otherwise, most aggregated proteins regain their shape and functionality following heat shock.
Cas9 Proofreads Gene Edits
Karen Zusi | Nov 13, 2015
The gene-editing CRISPR/Cas9 system has three checkpoints to ensure it alters the right section of DNA.
The Handedness of Cells
Kerry Grens | Jun 17, 2015
Actin—the bones of the cell—has a preference for swirling into a counterclockwise pattern.
Screening Goes In Silico
Carina Storrs | Feb 1, 2015
Computational tools take some of the cost—and guesswork—out of drug discovery.
RNA Puts Proteins in a Headlock
Kerry Grens | May 20, 2014
A noncoding RNA initiates translation by grabbing hold of repressor proteins and restricting their functions.
Toxin Evolution
Abby Olena | Jan 16, 2014
Researchers show that scorpion venom toxins are closely related to defensive proteins from venomous insects.
G-Protein Receptor Work Wins Nobel
Dan Cossins | Oct 9, 2012
Robert J. Lefkowitz and Brian K. Kobilka take home this year’s Nobel Prize for Chemistry for revealing how membrane receptors sense and respond to chemical signals.
Painting the Protein Atomic, 1961
Sabrina Richards | Aug 1, 2012
Irving Geis’s revolutionary painting of sperm whale myoglobin illuminated the nascent field of protein structure.