An illustration depicting pores on a membrane
DNA Nanopore Sequencing Adapted for Protein Sequence Comparisons
Researchers link a stretch of DNA to a peptide of interest and measure current changes as the molecule is pulled by a helicase through a nanopore.
ABOVE: © ISTOCK.COM, enot-poloskun
DNA Nanopore Sequencing Adapted for Protein Sequence Comparisons
DNA Nanopore Sequencing Adapted for Protein Sequence Comparisons

Researchers link a stretch of DNA to a peptide of interest and measure current changes as the molecule is pulled by a helicase through a nanopore.

Researchers link a stretch of DNA to a peptide of interest and measure current changes as the molecule is pulled by a helicase through a nanopore.

ABOVE: © ISTOCK.COM, enot-poloskun

proteins

Illustration of a DNA-peptide conjugate molecule being pulled through a nanopore in a membrane.
Infographic: Reading Proteins with Nanopores
Sophie Fessl | Feb 14, 2022
Adapting DNA nanopore sequencing to peptides allows researchers to identify single amino acid differences.
Q8W3K0, listed in the DeepMind database as a potential plant disease resistance protein from Arabidopsis thaliana
Predictions of Most Human Protein Structures Made Freely Available
Lisa Winter | Jul 23, 2021
The AlphaFold program from AI firm DeepMind has amassed a huge database of protein structures from humans and model organisms.
Recombinant proteins have a wide range of research and clinical applications.
Introducing Custom Recombinant Expression Services at the Cutting Edge of Biomolecular Engineering
The Scientist Creative Services Team, Sino Biological | Mar 24, 2022
A turnkey CRO service platform for recombinant protein and antibody expression and production
chrystal starbird
From Nature Lover to Structural Biologist: A Scientist’s Journey
Asher Jones | Feb 26, 2021
A gift of medical books from an unlikely source spurred Chrystal Starbird’s scientific career. She talks about what motivates her research on cell surface receptors and the obstacles she has faced as a Black woman in academia.
DeepMind AI Speeds Up the Time to Determine Proteins’ Structures
Lisa Winter | Dec 2, 2020
The technology solves proteins’ 3-D shapes in minutes, when traditional methods may take years.
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Probing Antibody Binding to the SARS-CoV-2 Spike Protein
The Scientist Creative Services Team in collaboration with Refeyn | Oct 29, 2021
Victor Yin will discuss two single-particle mass analysis methods that shed light on heterogenous, multimeric proteins and their interactions.
How a Centipede Survives its Own Species’ Venom
Shawna Williams | Nov 1, 2020
The same toxin targets different receptors in prey and conspecifics to deliver either a lethal or non-lethal blow.
Exploring the Matrix: A Profile of Zena Werb
Diana Kwon | Dec 1, 2019
The cell and molecular biologist unveiled a role for the breakdown of proteins in the extracellular matrix in both healthy and pathogenic cells.
Learn How to Accurately Determine Protein Conformation
Focus on Structure to Verify Protein Function
The Scientist Creative Services Team, RedShift Bio | Oct 6, 2021
Scientists analyze a therapeutic protein’s secondary structure to confirm drug efficacy and safety.
Image of the Day: Gnashers
Carolyn Wilke | Feb 18, 2019
A mollusk grows magnetic teeth so tough they can grind down rocks.  
Infographic: Triggering Titin
Julio M. Fernández | Sep 1, 2018
This third filament involved in muscle function is often ignored in medical textbooks. Here's how it works.
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Using Nanopores to Sense and Sequence Proteins
The Scientist Creative Services Team | Aug 30, 2021
Aleksei Aksimentiev and Stefan Howorka discuss challenges in amino acid sensing with nanopores and approaches to design efficient protein sequencing technology.
Infographic: Resurrecting Ancient Proteins
Amber Dance | Jul 1, 2018

Learn the basic steps researchers take when reconstructing proteins from the past and how these biomolecules can inform engineering projects.

Scientists Bring Ancient Proteins Back to Life
Amber Dance | Jul 1, 2018
Researchers are resurrecting proteins from millions of years ago to understand evolution and lay the groundwork for bioengineering custom molecules.
Form Determines Function: Insights from Structural Biology
The Scientist Creative Services Team | Jul 23, 2021
Researchers use diverse tools to analyze protein structures.
Image of the Day: Cell Dance 
The Scientist Staff, The Scientist Staff | Nov 24, 2017
Scientists develop a micropatterning device to study cell behavior. 
Oldest-Known Proteins?
Ben Andrew Henry | Sep 19, 2016
Molecules extracted from 3.8 million-year-old ostrich eggshells appear to break the record for oldest preserved proteins.
ELISA tips and tricks
Technique Talk: ELISA Tips and Tricks
The Scientist Creative Services Team | May 14, 2021
Learn to optimize ELISA experiments in this workshop.
Human Exomes Galore
Karen Zusi | Nov 16, 2015
A new database includes complete sequences of protein-coding DNA from 60,706 individuals.