A ball-and-stick plus ribbons molecular model of the hormone orexin, also known as hypocretin, isolated on a white background.
2023 Breakthrough Prizes Showcase Research in AI and Narcolepsy
Three prizes were awarded to six researchers working across the life sciences on cellular organization, protein structure, and the genetic underpinnings of a chronic sleep disorder.
2023 Breakthrough Prizes Showcase Research in AI and Narcolepsy
2023 Breakthrough Prizes Showcase Research in AI and Narcolepsy

Three prizes were awarded to six researchers working across the life sciences on cellular organization, protein structure, and the genetic underpinnings of a chronic sleep disorder.

Three prizes were awarded to six researchers working across the life sciences on cellular organization, protein structure, and the genetic underpinnings of a chronic sleep disorder.

proteins
An illustration depicting pores on a membrane
DNA Nanopore Sequencing Adapted for Protein Sequence Comparisons
Sophie Fessl | Feb 14, 2022
Researchers link a stretch of DNA to a peptide of interest and measure current changes as the molecule is pulled by a helicase through a nanopore.
Illustration of a DNA-peptide conjugate molecule being pulled through a nanopore in a membrane.
Infographic: Reading Proteins with Nanopores
Sophie Fessl | Feb 14, 2022
Adapting DNA nanopore sequencing to peptides allows researchers to identify single amino acid differences.
An immunoglobulin, also known as an antibody, floating in solution.
Shining a Light on Mass Photometry
The Scientist Creative Services Team and Refeyn
Mass photometry is an interferometric scattering-based technique offering researchers unprecedented characterization of biomolecular complexes and oligomerization in physiologically-relevant situations.
Q8W3K0, listed in the DeepMind database as a potential plant disease resistance protein from Arabidopsis thaliana
Predictions of Most Human Protein Structures Made Freely Available
Lisa Winter | Jul 23, 2021
The AlphaFold program from AI firm DeepMind has amassed a huge database of protein structures from humans and model organisms.
chrystal starbird
From Nature Lover to Structural Biologist: A Scientist’s Journey
Asher Jones | Feb 26, 2021
A gift of medical books from an unlikely source spurred Chrystal Starbird’s scientific career. She talks about what motivates her research on cell surface receptors and the obstacles she has faced as a Black woman in academia.
Recombinant proteins have a wide range of research and clinical applications.
Introducing Custom Recombinant Expression Services at the Cutting Edge of Biomolecular Engineering
The Scientist Creative Services Team and Sino Biological
A turnkey CRO service platform for recombinant protein and antibody expression and production
DeepMind AI Speeds Up the Time to Determine Proteins’ Structures
Lisa Winter | Dec 2, 2020
The technology solves proteins’ 3-D shapes in minutes, when traditional methods may take years.
How a Centipede Survives its Own Species’ Venom
Shawna Williams | Nov 1, 2020
The same toxin targets different receptors in prey and conspecifics to deliver either a lethal or non-lethal blow.
40679-ts-labtools-antibody-webinar-banner-jp800x560
Probing Antibody Binding to the SARS-CoV-2 Spike Protein
The Scientist Creative Services Team in collaboration with Refeyn
Victor Yin will discuss two single-particle mass analysis methods that shed light on heterogenous, multimeric proteins and their interactions.
Exploring the Matrix: A Profile of Zena Werb
Diana Kwon | Dec 1, 2019
The cell and molecular biologist unveiled a role for the breakdown of proteins in the extracellular matrix in both healthy and pathogenic cells.
Image of the Day: Gnashers
Carolyn Wilke | Feb 18, 2019
A mollusk grows magnetic teeth so tough they can grind down rocks.  
Learn How to Accurately Determine Protein Conformation
Focus on Structure to Verify Protein Function
The Scientist Creative Services Team and RedShift Bio
Scientists analyze a therapeutic protein’s secondary structure to confirm drug efficacy and safety.
Infographic: Triggering Titin
Julio M. Fernández | Sep 1, 2018
This third filament involved in muscle function is often ignored in medical textbooks. Here's how it works.
Infographic: Resurrecting Ancient Proteins
Amber Dance | Jul 1, 2018

Learn the basic steps researchers take when reconstructing proteins from the past and how these biomolecules can inform engineering projects.

800x560-sept-15-2021
Using Nanopores to Sense and Sequence Proteins
The Scientist Creative Services Team
Aleksei Aksimentiev and Stefan Howorka discuss challenges in amino acid sensing with nanopores and approaches to design efficient protein sequencing technology.
Scientists Bring Ancient Proteins Back to Life
Amber Dance | Jul 1, 2018
Researchers are resurrecting proteins from millions of years ago to understand evolution and lay the groundwork for bioengineering custom molecules.
Image of the Day: Cell Dance 
The Scientist Staff and The Scientist Staff | Nov 24, 2017
Scientists develop a micropatterning device to study cell behavior. 
Form Determines Function: Insights from Structural Biology
The Scientist Creative Services Team
Researchers use diverse tools to analyze protein structures.
Oldest-Known Proteins?
Ben Andrew Henry | Sep 19, 2016
Molecules extracted from 3.8 million-year-old ostrich eggshells appear to break the record for oldest preserved proteins.