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A medical professional, wearing light grey scrubs and white laboratory gloves, immunizes a patient, wearing a blue T-shirt, on their right upper arm.
| 5 min read
Since the invention of the first vaccine over two centuries ago, new discoveries have emerged to confer better protection.

smallpox

A transmission electron microscopic image of a tissue section containing variola virus particles, the pathogen responsible for causing smallpox in humans

Opinion: Destroy All Samples of the Smallpox Virus

A two-pronged needle, a glass vial of smallpox vaccine, and a syringe sit on a blue surface.

Smallpox Vaccine Recruits Skin Bacteria to Fight Disease

In one of the only known photos of Abraham Lincoln taken on the day of the Gettysburg Address, Lincoln can be seen seated, hatless, just below and to the right of the flag. Lincoln began developing symptoms of smallpox on the train home to Washington, DC.

Presidential Pox, 1863

black and white electron microscope image showing oval-shaped mature monkeypox virions as well as rounder immature ones

Texas Monkeypox Case Underscores Need for Better Surveillance

Introducing Inoculation, 1721

Epidemiologist Who Helped Eradicate Smallpox Dies

animal vaccinations being given at the Imperial Academy of Medicine in Paris

Bovine Inoculations, circa 1870s

Smallpox Kerfuffle Reveals Biosecurity Problems

CDC Lab Resumes After Safety Lapses

Trending

A team of cartoon scientists studying a giant pancreas.

Prolonged GLP-1 Exposure Remodels Gene Expression in the Pancreas by Flipping a Molecular Switch

A drawing of men and women holding boxes, resigning en mass from their jobs as editors.

Editors Mass Resign from Elsevier Journal After Editor-in-Chief Let Go

A magnifying glass, representing increased scrutiny into this student’s publication record, leans against a stack of papers.

Student Admits She Did Not Conduct Experiments in Now-Retracted Paper

Image of a Diploptera punctata cockroach.

Cockroach Milk Proteins Churn Out an Ig Nobel Win

Multimedia

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

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Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

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Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad
Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

bioxcell
Scientist reviewing cellular and molecular data on a computer in a laboratory.

Building Translation-Ready Biomarkers with Connected Workflows

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Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

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Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

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Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
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Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays