Participant’s Diagnosis Halts Gene Therapy Clinical Trial
Participant’s Diagnosis Halts Gene Therapy Clinical Trial
The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.
Participant’s Diagnosis Halts Gene Therapy Clinical Trial
Participant’s Diagnosis Halts Gene Therapy Clinical Trial

The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.

The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.

stem cell therapies
Cones Derived from Human Stem Cells Help Mice See: Study
Cones Derived from Human Stem Cells Help Mice See: Study
Marcus A. Banks | Apr 23, 2021
Researchers insert functioning cone photoreceptors into the retinas of mice with advanced eye disease, improving their vision.
Voters in California Extend Life of Stem Cell Funding Agency
Voters in California Extend Life of Stem Cell Funding Agency
Katarina Zimmer | Nov 13, 2020
The state will take on additional debt to finance CIRM, which will now continue to fund stem cell research, training, and clinical trials.
California Voters to Decide Future of Stem Cell Funding Agency
California Voters to Decide Future of Stem Cell Funding Agency
Katarina Zimmer | Oct 24, 2020
If approved, Proposition 14 would authorize the state to sell $5.5 billion in bonds to extend the life of CIRM, which funds stem cell research. The ballot measure has its critics.
Are Mesenchymal Stem Cells a Promising Treatment for COVID-19?
Are Mesenchymal Stem Cells a Promising Treatment for COVID-19?
Ruth Williams | Apr 9, 2020
As the first clinical data become available on treating coronavirus patients with the cells, scientists are equivocal about the rationale for the intervention.
Activation of the Immune System Underlies Cardiac Cell Therapies
Activation of the Immune System Underlies Cardiac Cell Therapies
Ruth Williams | Nov 27, 2019
A study in mice reveals that stem cell transplants, currently in clinical trials, may not actually require the cells.
Infographic: Light in the Dark
Infographic: Light in the Dark
Nicoletta Lanese | Oct 1, 2019
A new tool helps stem cells integrate with host neural circuitry after implantation in mice.
Stem Cell Funding Agency CIRM Is Nearly Out of Funds
Stem Cell Funding Agency CIRM Is Nearly Out of Funds
Chia-Yi Hou | Jul 8, 2019
The California Institute for Regenerative Medicine has been funding research since it formed in 2004, giving out nearly $3 billion in grants to date.
Clinical Trial Underway for a Natural Killer Cell Therapy
Clinical Trial Underway for a Natural Killer Cell Therapy
Chia-Yi Hou | May 7, 2019
The cells, derived from induced pluripotent stem cells, are in testing as an immunotherapy for cancer patients with solid tumors.
Donor-Derived iPS Cells Show Promise for Treating Eye Disease
Donor-Derived iPS Cells Show Promise for Treating Eye Disease
Jef Akst | Apr 30, 2019
Age-related macular degeneration patients who received injections of retinal cells derived from donors’ induced pluripotent stem cells have maintained their level of eyesight for a year.
Japan Approves iPS Cell Therapy Trial for Spinal Cord Injury
Japan Approves iPS Cell Therapy Trial for Spinal Cord Injury
Catherine Offord | Feb 18, 2019
The treatment will be tested in a handful of patients who suffered nerve damage in sports or traffic accidents.
Call to Stop Using the Term “Mesenchymal Stem Cell”
Call to Stop Using the Term “Mesenchymal Stem Cell”
Abby Olena | Sep 26, 2018
Critics say the misleading term actually refers to a heterogeneous population of cells, including possible tissue-specific progenitor cells and nonstem cells all lumped together.
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Katarina Zimmer | Jul 6, 2018
Stem-cell–derived natural killer cells engineered in a similar way to CAR-T cells may pave the way to “off the shelf” cancer therapies that aren’t patient-specific.
Dopamine Neuron Implants Ease Parkinson’s Symptoms in Monkeys
Dopamine Neuron Implants Ease Parkinson’s Symptoms in Monkeys
Sukanya Charuchandra | Jun 20, 2018
The stem cell–derived transplants were stable for 24 months and led to wide-ranging behavioral improvements in the monkeys.  
FDA Seeks to Block Two Unregulated Stem Cell Clinics
FDA Seeks to Block Two Unregulated Stem Cell Clinics
Jim Daley | May 11, 2018
Two patients became legally blind after receiving treatments at the facilities.
Can Young Stem Cells Make Older People Stronger?
Can Young Stem Cells Make Older People Stronger?
Shawna Williams | Dec 11, 2017
Small trials using younger donors and elderly recipients hint that mesenchymal stem cell transfers might reduce frailty. 
New FDA Pathway to Accelerate Development of Cell Therapies
New FDA Pathway to Accelerate Development of Cell Therapies
Jef Akst | May 22, 2017
Four products have already qualified for the regenerative medicine advanced therapy (RMAT) designation that provides extra interactions with the agency, and sooner.
First Clinic-Ready Stem Cell Repository
First Clinic-Ready Stem Cell Repository
Kerry Grens | Apr 6, 2017
The UK Stem Cell Bank offers several lines derived from human embryonic tissue.
Suicide Switch for Transplanted Stem Cells
Suicide Switch for Transplanted Stem Cells
Abby Olena | Mar 2, 2017
Researchers use an inducible gene to limit tumor growth from human iPSCs transplanted into mice.