SYNGAP1 helps neurons eliminate old synapses and form new ones after a novel experience (left and center left)—a process weakened in mice missing a copy of the gene (center right and right).
Autism-Linked Gene SYNGAP1 Molds Synaptic Plasticity, Learning
The finding may help to explain why people with SYNGAP1 mutations tend to have learning difficulties and a high tolerance for pain.
ABOVE: COURTESY OF GAVIN RUMBAUGH
Autism-Linked Gene SYNGAP1 Molds Synaptic Plasticity, Learning
Autism-Linked Gene SYNGAP1 Molds Synaptic Plasticity, Learning

The finding may help to explain why people with SYNGAP1 mutations tend to have learning difficulties and a high tolerance for pain.

The finding may help to explain why people with SYNGAP1 mutations tend to have learning difficulties and a high tolerance for pain.

ABOVE: COURTESY OF GAVIN RUMBAUGH
SYNGAP1

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