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3D rendered medical illustration of T cells trying to subdue cancer cells.
How Tumors Tire Out T Cells
Researchers investigated how cancer antigenicity drives unique forms of T cell exhaustion and hypofunctionality.
How Tumors Tire Out T Cells
How Tumors Tire Out T Cells

Researchers investigated how cancer antigenicity drives unique forms of T cell exhaustion and hypofunctionality.

Researchers investigated how cancer antigenicity drives unique forms of T cell exhaustion and hypofunctionality.

T cell exhaustion

News feature
Vector image of black body with head surrounded by white clouds
Multiple Possible Causes of Long COVID Come into Focus
Natalia Mesa, PhD | Sep 28, 2022 | 10+ min read
Recent studies have lent support for a variety of hypotheses explaining the debilitating symptoms affecting millions of people after SARS-CoV-2 infection.  
3D rendered images of three T cell
T Cells Ward Off Aging with Help from Their Friends
Natalia Mesa, PhD | Sep 16, 2022 | 5 min read
Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.
The Epigenetic Landscape During T Cell Exhaustion
The Epigenetic Landscape During T Cell Exhaustion
The Scientist and 10x Genomics | Jul 6, 2022 | 1 min read
In this webinar, E. John Wherry and Debattama Sen will discuss how epigenetic scarring of exhausted T cells influences chronic infections.
A Spotlight on T Cell Exhaustion
A Spotlight on T Cell Exhaustion
The Scientist | Feb 8, 2022 | 1 min read
Mary Philip and Benjamin Youngblood discuss how T cell exhaustion affects cancer progression and immunotherapy efficacy.
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