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Illustration of the VPM1002 whole-cell vaccine and resulting immune response
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
Infographic: TB Vaccines in the Pipeline Take Varied Approaches

More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  

More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  

TB

False-colored micrograph of Mycobacterium tuberculosis
Tuberculosis: The Forgotten Pandemic
Anthony King | Jul 1, 2021 | 10+ min read
This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.
Bile and Potatoes, 1921
Jef Akst | Apr 1, 2021 | 3 min read
One hundred years after its invention, BCG has stood the test of time as a vaccine against tuberculosis.
bcg tuberculosis tb sars-cov-2 covid-19 coronavirus pandemic vaccine nonspecific effects trained immunity innate immune system response
An Old TB Vaccine Finds New Life in Coronavirus Trials
Anthony King | May 4, 2020 | 8 min read
Studies are underway to test whether giving a shot of BCG vaccine could protect doctors and nurses against COVID-19.
Experimental TB Vaccine Partially Effective: Study
Ashley Yeager | Oct 30, 2019 | 2 min read
Tested in patients with the latent form of tuberculosis, the vaccine prevented the development of the active form of infection in 50 percent more individuals compared with unvaccinated patients.
Triage Test for Tuberculosis Spots Infections Within an Hour
Ruth Williams | Oct 23, 2019 | 4 min read
An early-stage, blood-based assay shows potential as a method for sorting patients with suspected TB from those with other respiratory illnesses.
First New Tuberculosis Drug Approved in 50 Years
Jef Akst | Aug 15, 2019 | 2 min read
The US Food and Drug Administration green lights a therapy for an extreme form of multidrug resistant TB.
Opinion: Why Warthogs Are Useful in Figuring Out How Bovine TB Spreads
Eduard Roos | Mar 12, 2019 | 4 min read
The information we’ve gathered showed us that warthogs can be used as disease sentinels, avoiding the need to resort to testing valuable or endangered animals.
Lab in South African “Township” to Sample TB from Breathed Air
Linda Nordling | Mar 8, 2019 | 5 min read
A new facility located in a congested community with high tuberculosis rates brings basic science and cutting edge techniques into the heart of disease circulation.
WHO: TB’s Toll Worse Than Thought
Bob Grant | Oct 22, 2014 | 1 min read
A new report from the World Health Organization finds that tuberculosis has infected hundreds of thousands more people around the world than was estimated a year ago.
Outwitting the Perfect Pathogen
Megan Scudellari | Jan 1, 2014 | 8 min read
Tuberculosis is exquisitely adapted to the human body. Researchers need a new game plan for beating it.
TB Vaccine Protects Against MS
Jef Akst | Dec 10, 2013 | 1 min read
A vaccine developed to ward off tuberculosis may help prevent symptoms of multiple sclerosis, according to a new study.
Week in Review, May 20–24
Bob Grant | May 24, 2013 | 4 min read
Journals plagiarizing journals; new immune cells combat diabetes; TB-killing vitamin C; analog cell computers; real time fish memory; ant-pitcher plant mutualism
Vitamin C Slays TB Bacteria
Dan Cossins | May 21, 2013 | 3 min read
The essential nutrient can kill drug-resistant Mycobacterium tuberculosis by producing oxidative radicals that damage DNA.
Stem Cells: Safe Haven For TB
Nsikan Akpan | Feb 5, 2013 | 3 min read
Tuberculosis bacteria find shelter from drugs and the body’s defenses in bone marrow stem cells.
Pneu-mummy-a
Hayley Dunning | Nov 1, 2012 | 4 min read
Comparing the protein profile of a 500-year-old Inca mummy to modern humans reveals an active lung infection prior to sacrifice.
 
Mummy's Little Secret
Hayley Dunning | Oct 31, 2012 | 1 min read
Preserved remains from the Andes yield clues about infectious diseases.
Sniffing Out TB
Jef Akst | Oct 17, 2012 | 2 min read
An African rat helps detect tuberculosis in Tanzania, prompting the Mozambique government to pursue a similar project.
Beating Drug-Resistant TB
Ruth Williams | Sep 19, 2012 | 3 min read
Reinvestigating a natural antibiotic compound reveals its potential as a tuberculosis drug.
Double-Edged TB Drug
Beth Marie Mole | Sep 12, 2012 | 1 min read
A cheap pain reliever that can kill drug-resistant, tuberculosis-causing bacteria may never be tested.
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