Experimental TB Vaccine Partially Effective: Study

Tested in patients with the latent form of tuberculosis, the vaccine prevented the development of the active form of infection in 50 percent more individuals compared with unvaccinated patients.

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ABOVE: Macrophages consume M. tuberculosis in the lung in this illustration. ©ISTOCK.COM, SELVANEGRA

An experimental vaccine continues to show promise in preventing active tuberculosis infections in patients with the latent form of the disease, researchers reported yesterday (October 29) in The New England Journal of Medicine and at the 50th Union World Conference on Lung Health conference.

“The vaccine looks promising, and likely better than our century-old BCG [bacille Calmette-Guerin] vaccine,” Mario Raviglione, a global health expert at the University of Milan who headed the World Health Organization’s (WHO) global tuberculosis program from 2003 to 2017, tells The New York Times.

The BCG vaccine is typically given to children in countries where the prevalence of TB is high. It is rarely given to adults because it varies in effectiveness in preventing Mycobacterium tuberculosis, the bacterium that causes the illness, from multiplying and causing disease in the lungs.

Tuberculosis is now ...

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Meet the Author

  • Ashley Yeager

    Ashley started at The Scientist in 2018. Before joining the staff, she worked as a freelance editor and writer, a writer at the Simons Foundation, and a web producer at Science News, among other positions. She holds a bachelor’s degree in journalism from the University of Tennessee, Knoxville, and a master’s degree in science writing from MIT. Ashley edits the Scientist to Watch and Profile sections of the magazine and writes news, features, and other stories for both online and print.

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