Infographic: TB Vaccines in the Pipeline Take Varied Approaches
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
Infographic: TB Vaccines in the Pipeline Take Varied Approaches

More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  

More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  

tuberculosis
Tuberculosis: The Forgotten Pandemic
Tuberculosis: The Forgotten Pandemic
Anthony King | Jul 1, 2021
This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.
Bile and Potatoes, 1921
Bile and Potatoes, 1921
Jef Akst | Apr 1, 2021
One hundred years after its invention, BCG has stood the test of time as a vaccine against tuberculosis.
AI-Assisted Cough Tracking Could Help Detect the Next Pandemic
AI-Assisted Cough Tracking Could Help Detect the Next Pandemic
Max Kozlov | Dec 6, 2020
Some researchers have turned their focus to artificial intelligence to study an underused symptom common to most respiratory pathogens—cough.
Infographic: How Vaccines Train Innate Immunity
Infographic: How Vaccines Train Innate Immunity
Shawna Williams | Nov 1, 2020
A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.
How Some Vaccines Protect Against More than Their Targets
How Some Vaccines Protect Against More than Their Targets
Shawna Williams | Nov 1, 2020
As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.
An Old TB Vaccine Finds New Life in Coronavirus Trials
An Old TB Vaccine Finds New Life in Coronavirus Trials
Anthony King | May 4, 2020
Studies are underway to test whether giving a shot of BCG vaccine could protect doctors and nurses against COVID-19.
Artificial Intelligence Discovers Potent Antibiotic
Artificial Intelligence Discovers Potent Antibiotic
Amy Schleunes | Feb 22, 2020
Researchers used a machine-learning platform to test more than 100 million molecules for antibacterial activity.
Experimental TB Vaccine Partially Effective: Study
Experimental TB Vaccine Partially Effective: Study
Ashley Yeager | Oct 30, 2019
Tested in patients with the latent form of tuberculosis, the vaccine prevented the development of the active form of infection in 50 percent more individuals compared with unvaccinated patients.
Triage Test for Tuberculosis Spots Infections Within an Hour
Triage Test for Tuberculosis Spots Infections Within an Hour
Ruth Williams | Oct 23, 2019
An early-stage, blood-based assay shows potential as a method for sorting patients with suspected TB from those with other respiratory illnesses.
First New Tuberculosis Drug Approved in 50 Years
First New Tuberculosis Drug Approved in 50 Years
Jef Akst | Aug 15, 2019
The US Food and Drug Administration green lights a therapy for an extreme form of multidrug resistant TB.
Genetically Modified Viral Cocktail Treats Deadly Bacteria in Teen
Genetically Modified Viral Cocktail Treats Deadly Bacteria in Teen
Ashley Yeager | May 8, 2019
Tweaking the genomes of two phages and combining them with a third phage helped to clear a persistent Mycobacterium infection in the patient.
Tuberculosis Can Emerge After Cancer Immunotherapy
Tuberculosis Can Emerge After Cancer Immunotherapy
Ashley Yeager | Apr 1, 2019
At least a handful of patients have developed active TB after receiving cancer treatment designed to boost the immune system’s antitumor response.
Opinion: Why Warthogs Are Useful in Figuring Out How Bovine TB Spreads
Opinion: Why Warthogs Are Useful in Figuring Out How Bovine TB Spreads
Eduard Roos | Mar 12, 2019
The information we’ve gathered showed us that warthogs can be used as disease sentinels, avoiding the need to resort to testing valuable or endangered animals.
Lab in South African “Township” to Sample TB from Breathed Air
Lab in South African “Township” to Sample TB from Breathed Air
Linda Nordling | Mar 8, 2019
A new facility located in a congested community with high tuberculosis rates brings basic science and cutting edge techniques into the heart of disease circulation.
Investigation Questions Transparency for Failed TB Vax
Investigation Questions Transparency for Failed TB Vax
Jef Akst | Jan 11, 2018
The BMJ inquiry finds that researchers presented only select results from animal experiments when applying for funding and approval for human trials.
Urine Test for TB Yields Results in 12 Hours
Urine Test for TB Yields Results in 12 Hours
Jef Akst | Dec 13, 2017
The new test could improve upon two current methods to diagnose tuberculosis—a skin test or culturing bacteria from saliva, both of which take days.
Toward Breaking the Cold Chain
Toward Breaking the Cold Chain
Kerry Grens | Jan 24, 2017
Research efforts aim to obviate the need for vaccine refrigeration.
The Badger-Cow TB Connection
The Badger-Cow TB Connection
Bob Grant | Aug 5, 2016
Researchers in the U.K. report that badgers may be passing tuberculosis to farm animals not through direct contact, as was previously suspected, but through exposure to urine and feces.