First Human Genome Sequenced from Ancient Pompeii

The genome is from a male who was likely in his late thirties when the historic Mount Vesuvius eruption occurred. The analyses suggest he is related to the diverse Imperial Roman population of the time, and that he may have suffered from spinal tuberculosis.

Written byAlejandra Manjarrez, PhD
| 4 min read
A drawing portraying the black silhouette of Pompeii buildings with Mount Vesuvius and the sky behind them
Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

The city of Pompeii—buried by an eruption of Mount Vesuvius in 79 CE—has been intensively studied for decades. The sudden tragedy transformed it into a glimpse of life during the Roman Imperial Age, frozen in time, which has yielded novel insights into the architecture, customs, and language of the era. But one goal has remained out of reach: sequencing the whole genome of any Pompeian. Scientists have been attempting to do so for years in the hopes of learning more about the population who once lived there, for example, where they came from, or what diseases they suffered from.

Now, thanks to improved genomic technologies and interdisciplinary collaboration, a diverse group of researchers has finally achieved the feat. They announce today (May 26) in Scientific Reports the bioarchaeological and genomic analyses of two adults (a man and a woman) found at a Pompeii building named Casa del Fabbro, translated as ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • alejandra manjarrez

    Alejandra Manjarrez is a freelance science journalist who contributes to The Scientist. She has a PhD in systems biology from ETH Zurich and a master’s in molecular biology from Utrecht University. After years studying bacteria in a lab, she now spends most of her days reading, writing, and hunting science stories, either while traveling or visiting random libraries around the world. Her work has also appeared in Hakai, The Atlantic, and Lab Times.

    View Full Profile
Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies