Conceptual image of blue neurons with glowing segments over blue background.
CRACK Method Reveals Novel Neuron Type in Mouse Brain
A new technique reveals cells’ precise locations and functions in the brain. Its developers have already used it to identify a previously unknown neuron type.
ABOVE: © istock.com, ismagilov
CRACK Method Reveals Novel Neuron Type in Mouse Brain
CRACK Method Reveals Novel Neuron Type in Mouse Brain

A new technique reveals cells’ precise locations and functions in the brain. Its developers have already used it to identify a previously unknown neuron type.

A new technique reveals cells’ precise locations and functions in the brain. Its developers have already used it to identify a previously unknown neuron type.

ABOVE: © istock.com, ismagilov

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Illustration showing how calcium imaging and HCR-FISH combined is a technique called comprehensive readout of activity and cell type markers (CRACK)
Infographic: Simultaneously Studying Neuron Structure and Function
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A new methodology combines existing techniques to reveal the specific function and location of multiple types of neurons at once.
Enter Our 2021 Top 10 Innovations Contest
The Scientist Staff | Jun 10, 2021
Submit your new product now to have a chance at being selected for a coveted spot in The Scientist’s 2021 competition.
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illustration of people using social media on various electronic devices
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Emma Yasinski | Jan 6, 2020
Scientists are using social media to track diseases and understand how people respond to them.
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A group of epidemiologists and computer scientists built a system to mine various online sources for keywords suggesting disease outbreaks.
Worm Embryogenesis: Cell by Cell and Gene by Gene
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A single-cell map of C. elegans’s transcriptome during development finds cell lineages that start out genetically different and end up as cells of similar function and genetic profile.
c. elegans sleep microfluidics
Microfluidic Chambers Trigger Sleep in C. elegans
Alejandra Manjarrez | Nov 19, 2019
This newly described behavior occurs spontaneously, but can be modulated by food availability, temperature, and the size of the chambers.
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Conflicting results on the existence of new neurons in adults have researchers designing new ways to identify and count neuronal progenitors—and finally get to the bottom of neurogenesis.
New Tissue Clearing Methods Offer a Window into the Brain
Andy Tay | Oct 1, 2019
Researchers are developing a variety of approaches for clearing neural tissue to get a better view of the brain’s circuitry.
Extended Until August 19: Enter Our Top 10 Innovations Contest Today
The Scientist Staff | Aug 12, 2019
Submit your new product by the end of the day Monday to have a chance at being selected for a coveted spot in The Scientist's 2019 competition.
A Brief Guide to the Current CRISPR Landscape
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Hundreds of CRISPR patents have been granted around the world, and the number of applications continues to grow at a rapid pace.
USPTO Restarts CRISPR Patent Dispute Between Broad and UC
Jef Akst | Jun 26, 2019
The US patent office declares an interference between the intellectual property held by the Broad Institute and several patent applications filed by the University of California—opposite its previous ruling.
A Toolmaker
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artificial intelligence feature the scientist
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AI mice in labs
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