2022 Top 10 Innovations 
| 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.

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Last Chance to Enter Our Annual Top 10 Innovations Contest

Conceptual image of blue neurons with glowing segments over blue background.

CRACK Method Reveals Novel Neuron Type in Mouse Brain

Illustration showing how calcium imaging and HCR-FISH combined is a technique called comprehensive readout of activity and cell type markers (CRACK)

Infographic: Simultaneously Studying Neuron Structure and Function

Enter Our 2021 Top 10 Innovations Contest

Conch Horn Finds Its Song Again After 17,000 Years

Snappy Acronyms Generate Excitement for Science (SAGES)

Infographic: How a City Health Department Uses Social Media

illustration of people using social media on various electronic devices

Can Social Media Inform Public Health Efforts?

Infographic: How HealthMap Tracks Disease

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A close-up image of a fly landing on a dessert

What Happens When a Fly Lands on Your Food? 

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Red and green small tomatoes. A new genetic engineering approach helped gene-edited plants grow faster.

Gene-Edited Crops Grow Faster with a Little Help from Bacteria

Image of an infant’s feet that are visible in a hospital incubator.

Record-Breaking DNA Sequencing Technology Could Transform Newborn Care

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Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

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Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

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Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

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LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

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Evosep Unveils Open Innovation Initiative to Expand Standardization in Proteomics

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OGT expands MRD detection capabilities with new SureSeq Myeloid MRD Plus NGS Panel