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| 10 min read
To tackle a backlog in toxicity testing, US federal scientists are modernizing programs with high-throughput assays and AI. 

toxicology

Discover how to select the optimal viability assay to match a research question

A Life-or-Death Situation: Determining Cell Viability

Remove a Common Source of Experimental Error

Reducing Risk in Therapeutic Drug Treatment and Monitoring

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Understanding Our Enemies: Identifying Mechanisms of Antibiotic Resistance

The Community-Wide Effort to Standardize QA/QC for Metabolomics and Lipidomics

Bald Eagle Killer Identified

Perfecting Dose Response Assays

Q&A: Tire Rubber Preservative Harms Coho Salmon, Study Suggests

EPA Science Board Criticizes Proposed Regulatory Rollbacks

Janette Sherman, Public Health Activist, Dies

EPA Aims to Drastically Reduce Animal Testing

Fixing the Flaws in Animal Research

Sunscreen Ingredients Absorbed into Blood: Study

computing a cure

Artificial Intelligence Shakes Up Drug Discovery

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Humane Society Successfully Campaigns to End Pesticide Test on Dogs

cans of food, seen from the top

A Landmark Study On BPA Leaves Scientists at Odds

Software-Based Chemical Screen Could Minimize Animal Testing

EPA to Limit Assessments of Toxic Chemical Risks

Bees’ Molecular Responses to Neonicotinoids Determined

Nasser Zawia: An American Scientist Born in Yemen

Will Organs-in-a-Dish Ever Replace Animal Models?

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Image of Atul Butte.

Biomedical Informatician Atul Butte Dies at 55

An illustration showing the accumulation of amyloid plaques between nerve cells, which is the underlying cause of disorders like Alzheimer’s and Parkinson’s disease.

A Gut Pathogen’s Unexpected Weapon Against Amyloid Diseases

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Two domesticated animals, a red border collie dog and horse together at sunset.

The Genes That Shaped Pets and Domesticated Livestock

Multimedia

Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

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Two images of U2OS cells transfected with a fluorescently labeled protein. The left panel shows AI-based analysis of transfection efficiency, with cells bounded in yellow and label marked in magenta. The right panel shows baseline fluorescence.

Leveraging AI for Analyzing Cell Transfection Efficiency

Image of small blue creatures called Nergals. Some have hearts above their heads, which signify friendship. There is one Nergal who is sneezing and losing health, which is denoted by minus one signs floating around it.
June 2025, Issue 1

Nergal Networks: Where Friendship Meets Infection

A citizen science game explores how social choices and networks can influence how an illness moves through a population.

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Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

Twist Bio 
Illustrated plasmids in bright fluorescent colors

Enhancing Elution of Plasmid DNA

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An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

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Explore new strategies for improving plasmid DNA manufacturing workflows.

Overcoming Obstacles in Plasmid DNA Manufacturing

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Products

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Waters Enhances Alliance iS HPLC System Software, Setting a New Standard for End-to-End Traceability and Data Integrity 

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Agilent Unveils the Next Generation in LC-Mass Detection: The InfinityLab Pro iQ Series

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Agilent Announces the Enhanced 8850 Gas Chromatograph

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Pioneering Cancer Plasticity Atlas will help Predict Response to Cancer Therapies