toxicology

After a nearly 30-year hunt, researchers have shown that a neurotoxin generated by cyanobacteria on invasive plants is responsible for eagle and waterbird deaths from vacuolar myelinopathy.

6PPD, a tire preservative, reacts with ozone to produce a compound that the researchers say may be responsible for large die-off events.

Most of the panel’s members were appointed by the Trump administration.

The physician, toxicologist, and expert witness drew attention to health issues caused by radiation and toxic chemicals.

The agency plans to stop funding virtually all toxicology studies in mammals by 2035.

Many preclinical studies carried out in vivo are poorly designed and generate irreproducible data, but efforts to address the problem are on the rise.

FDA researchers report that multiple active ingredients wind up in users’ bloodstream and recommend toxicology testing to investigate the clinical significance of the findings.

The pharmaceutical industry is looking to machine learning to overcome complex challenges in drug development.

After the release of an undercover investigation, Corteva Agrisciences announces it will release 36 beagles for rehoming.

Conceived as a way to resolve differences between government regulators and academics over the chemical’s effects, the CLARITY-BPA collaboration instead highlights divisions.

Researchers develop a machine-learning tool for toxicity analyses that is more consistent in predicting chemical hazards than assays on animals.

Reducing the evaluation to only direct contact, rather than including environmental exposures, could leave damaging substances on the market, critics say.

Researchers pinpoint a protein that can metabolize at least one of the insecticides, highlighting a route to identifying compounds that are friendlier to the critical pollinators.

The University of Rhode Island neurotoxicologist and dean came to the U.S. for college in the 1980s. 

Increasingly sophisticated tissue organoids can model many aspects of disease, but animal studies retain a fundamental role in research, scientists say. 

Exposing male rats to nonionizing radiation increased the animals’ risk of brain and heart tumors in a study, but the findings are far from conclusive.