transgenic mice
Surrogate Genes Enable Reproduction
Surrogate Genes Enable Reproduction
Jyoti Madhusoodanan | Jan 28, 2016
Increasing the expression of two genes from non-Y chromosomes restores spermatogenesis in male mice that lack Y chromosomes.
Citation Payola?
Citation Payola?
Bob Grant | Aug 18, 2015
A transgenic mouse company is paying researchers who mention its animal models in scientific papers.
Passenger Mutations Can Skew Results
Passenger Mutations Can Skew Results
Kate Yandell | Jul 7, 2015
Some genetically engineered mice harbor unwanted mutations that hitchhike alongside desired modifications, affecting experimental outcomes.
Visualizing X Chromosome Inactivation
Visualizing X Chromosome Inactivation
Abby Olena | Jan 21, 2014
Researchers develop mouse lines to help them see whether the maternal or paternal X chromosome is inactivated.
Sperm on Lockdown
Sperm on Lockdown
Abby Olena | Dec 4, 2013
In a proof-of-principle study, genetic deletion of two genes renders male mice infertile by preventing sperm transport through the vas deferens.
More-Primitive Stem Cells Produced
More-Primitive Stem Cells Produced
Kate Yandell | Sep 11, 2013
Reprogramming cells within live mice yields a new type of induced pluripotent stem cell.
Cranking Out New Models
Cranking Out New Models
Kate Yandell | May 6, 2013
Scientists make mice strains with multiple mutations in less than a month without using embryonic stem cells.
Speaking of Science
Speaking of Science
The Scientist Staff | May 1, 2013
May 2013's selection of notable quotes
Review: <em>Errors of the Human Body</em>
Review: Errors of the Human Body
Jef Akst | Apr 11, 2013
This dramatic science fiction film follows a grieving father using his research to understand his infant son’s gruesome death—and explores the culture and ethics of science along the way.
Flickering Neurons
Flickering Neurons
Ruth Williams | Feb 1, 2013
Fluorescent calcium sensors in transgenic mice give a real-time readout of neuronal activity.