CAR T cells, oncolytic virus, CD19, mouse model, solid cancer, liquid cancer, tumor, immune response, immunotherapy, T cell, treatment
Immunotherapy Combo Reduces Solid Tumors in Mice
When tumor cells are infected with an oncolytic virus carrying a modified CD19 gene, they become targets for CAR T cells engineered to recognize this molecular marker.
Immunotherapy Combo Reduces Solid Tumors in Mice
Immunotherapy Combo Reduces Solid Tumors in Mice

When tumor cells are infected with an oncolytic virus carrying a modified CD19 gene, they become targets for CAR T cells engineered to recognize this molecular marker.

When tumor cells are infected with an oncolytic virus carrying a modified CD19 gene, they become targets for CAR T cells engineered to recognize this molecular marker.

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tumor heterogeneity
Infographic: Researchers Take Aim at Cancer Evolution
Catherine Offord | Apr 1, 2020
Strategies to trick, manipulate, and direct the evolution of tumors
Cancer Researchers Use Evolution to Target Drug Resistance
Catherine Offord | Apr 1, 2020
New therapeutic approaches in oncology aim to manipulate or block cancer’s adaptation to treatment.
The Scientist on the Pulse, April 23
Kerry Grens | Apr 23, 2015
Hot topics in cancer research from the annual meeting of the American Association for Cancer Research
To Each His Own
Mary Beth Aberlin | Apr 1, 2015
Cancer treatment becomes more and more personal.
Opinion: Overcoming Cancer’s Complexities
Daniel S. Kapp, David Rubenson, Beverly Mitchell | Apr 11, 2014
Considering “targeted therapeutics” in the face of intra-patient heterogeneity. 
Cancer Clinical Trials of Tomorrow
Tomasz M. Beer | Apr 1, 2013
Advances in genomics and cancer biology will alter the design of human cancer studies.
Up, Up, and Array
Megan Scudellari | Apr 1, 2013
By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.
Cancer More Diverse than Its Genetics
Ruth Williams | Dec 13, 2012
Tumor cells can exhibit different behaviors despite being genetically indistinguishable.
An Epi Phenomenon
Karen Hopkin | Dec 1, 2012
While exploring the genetics of a rare type of tumor, Stephen Baylin discovered an epigenetic modification that occurs in most every cancer—a finding he’s helping bring to the clinic.