Fluorescence microscopy image of a human small intestine organoid stained with Ki67 and EpCAM antibodies and DAPI (scale bar represents 100 micrometers).
| 3 min read
Choosing the right 3D culture components and validation steps helps researchers unlock accurate, reproducible, and relevant insights into cancer biology.
Sino

tumor heterogeneity

Image of spatial transcriptomic spots superimposed onto a stained tissue section.

Poor Cancer Prognosis Associated with a Transcriptional Signature

Understanding How Single Cell Evolution Drives Tumor Complexity

Understanding How Single Cell Evolution Drives Tumor Complexity

A colorful image of a tumor

Opinion: Stopping the Cancer Cells that Thrive on Chemotherapy

Pink- and purple-stained cells clustered into glands

Phenotypic Variation in Cancer Cells Often Not Due to Mutations

A purple-stained section of an invasive breast cancer growth. The dark purple non-fatty tissue takes up the majority of the frame, and pale purple circular tumors grow in ducts in the bottom left.

Harboring Hard and Soft Cells Lets Tumors Grow and Metastasize Simultaneously

Photograph of Humsa Venkatesh

Humsa Venkatesh Probes Cancer’s Grip on the Brain

Explore single cell and spatial methods for studying cancer biology

Analyzing Multiple Dimensions of Cancer Biology

Diffuse star-like shapes with regions in purple, green, and both colors overlapped.

Tumor Cells on Brink of Death May Trigger Metastasis

Stem Cells in Human Teeth Follow the Rules of Their Environment

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An old medical illustration features the ear in the center with nerves of the head shown in yellow.

The Ear as a Therapeutic Gateway to the Vagus Nerve

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

3D illustration showing three differently colored semi-translucent cells, representing different T cell subtypes, on a black background. A purple cell is in the front on the right, a red cell is on the left, and a blue cell sits behind the red one.

T Cell Nomenclature Gets an Update

A yellow-colored frozen frog.

Freeze-Tolerant Frogs Power Organ Cryopreservation Strategies

Multimedia

Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

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Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

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Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

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BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

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Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

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VANTAstar Flexible microplate reader with simplified workflows

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