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3D Illustration of X shaped chromosomes in blue
X Chromosome Silenced in Some Cancers in Males
A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 
X Chromosome Silenced in Some Cancers in Males
X Chromosome Silenced in Some Cancers in Males

A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 

A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 

X chromosome inactivation
Infographic: How Some X-Chromosome Genes Escape Inactivation
Amber Dance | Mar 1, 2020 | 2 min read
About one-quarter of the hundreds of genes on the inactivated X chromosome in XX cells manage to escape that silencing, at least some of the time.
Genes that Escape Silencing on the Second X Chromosome May Drive Disease
Amber Dance | Mar 1, 2020 | 10+ min read
When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity.
Switch Master: A Profile of Barbara Meyer
Diana Kwon | Jan 13, 2020 | 9 min read
Working with bacteriophages and nematodes, the University of California, Berkeley, molecular biologist uncovered a role for genetic switches in early development.
cancer more common in men
Why Is Cancer More Common in Men Than in Women?
Jef Akst | Apr 1, 2019 | 4 min read
The molecular processes that lead males to be more susceptible to the disease are only beginning to come to light.
X Marks the Sex-Skewed Spot
Rina Shaikh-Lesko | Mar 7, 2016 | 2 min read
Alterations in epigenetic markers on the X chromosome may be why males outnumber females among murine offspring bred through in vitro fertilization.
Legacies Left Behind in 2015
Karen Zusi | Dec 30, 2015 | 5 min read
A look at the contributions of some of the prominent researchers who died this year
X Inactivation Discoverer Dies
Jenny Rood | Jan 9, 2015 | 2 min read
British geneticist Mary Lyon has passed away at age 89.
DNA Loop-the-Loops
Kate Yandell | Dec 11, 2014 | 4 min read
A new full-genome map indicates how DNA is folded within the nuclei of human cells.
Week in Review: January 20–24
Tracy Vence | Jan 23, 2014 | 3 min read
Mistimed sleep disrupts human transcriptome; canine tumor genome; de novo Drosophila genes; UVA light lowers blood pressure; aquatic microfauna fight frog-killing fungus
Visualizing X Chromosome Inactivation
Abby Olena, PhD | Jan 21, 2014 | 2 min read
Researchers develop mouse lines to help them see whether the maternal or paternal X chromosome is inactivated.
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