Where is a scientist to begin studying a newly cloned gene that has no apparent function or phenotype? A common approach for obtaining functional clues is to inactivate the gene either in vitro or in vivo and observe the outcome. Antisense technology provides a powerful technique to study the functional consequences of gene silencing without deleting the gene altogether.
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In 1997 GENE TOOLS was founded as the only commercial source for research quantities of "Morpholino" oligos. The constituents of these chains differ from...
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