The Ears Have It

A teaching obligation in graduate school introduced James Hudspeth to a career focused on how vertebrates sense sounds.

Written byAnna Azvolinsky
| 9 min read

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A. James Hudspeth
Professor of Neuroscience, Rockefeller University Investigator, Howard Hughes Medical Institute
ZACH VEILLEUX, DIRECTOR OF PUBLICATIONS & EDITOR-IN-CHIEF, COMMUNICATIONS AND PUBLIC AFFAIRS, THE ROCKEFELLER UNIVERSITY
When he was 11 and 12, James Hudspeth spent his summers working in a Texas law firm, a job arranged by his lawyer father. But Hudspeth already knew he would never become an attorney. “I’ve been a scientist as long as I can remember,” he says. He pleaded with his parents to find him a job with a science bent and spent the following three summers working for his first scientific mentor—Peter Kellaway, a neurophysiologist at Baylor College of Medicine. “He was a stunning role model for a kid. I was very impressed by his seriousness and his sense of purpose.” Hudspeth worked first as a histology technician and then in an electronics shop, soldering EEG electrodes for use in medical school courses.

The jobs also gave Hudspeth a sneak peek at medicine in action. During his lunch break, he would surreptitiously sneak up into the observation dome above the hospital’s surgical theater and watch open-heart surgery while he ate his lunch. “It was so grand. This was the hospital where open-heart surgery techniques were pioneered,” says Hudspeth. “There were four surgical theaters, and surgeon Michael DeBakey would go clockwise from room to room doing the critical parts of surgeries. I would tag along with my sandwich. Fourteen-year-olds were not supposed to be there, and especially not eating a tuna sandwich!”

“The hope is that we can restore hearing in humans by regenerating hair cells in our own ears, basically by hijacking the molecular program that made the ...

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    Anna Azvolinsky received a PhD in molecular biology in November 2008 from Princeton University. Her graduate research focused on a genome-wide analyses of genomic integrity and DNA replication. She did a one-year post-doctoral fellowship at Memorial Sloan Kettering Cancer Center in New York City and then left academia to pursue science writing. She has been a freelance science writer since 2012, based in New York City.

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