The Mummy Code

Ancient-DNA researchers have long clashed over work on Egyptian mummies, but next-gen sequencing might resolve their debates.

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KING TUT UNMASKED: Can next-gen sequencing help researchers unwrap the secrets of ancient pharaohs?STEVE EVANS/WIKIMEDIA COMMONS

In 2010, researchers analyzed DNA from the ancient Egyptian boy-king Tutankhamen and 10 of his relatives (JAMA, 303:638-47). It was a blockbuster study. Revealing family relationships among the 3,300-year-old royals and identifying the malaria parasite Plasmodium falciparum in several of the corpses, the research grabbed headlines and was even the subject of a 3-part documentary aired by the Discovery Channel, which partly funded the project.

But the work drew criticism from some ancient-DNA experts, who claimed that the results could be explained by contamination from modern humans. The ensuing row deepened a long-standing rift among researchers who aim to coax genetic secrets from the mummified denizens of bygone civilizations. “For sure it is a highly debated field,” says Carsten Pusch of the University of Tübingen ...

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