The following recommendations of the National Institutes of Health's Rating of Grant Applications (RGA) committee are taken from NIH's World Wide Web page (, where the committee's entire report is available. Comments may be sent to

  1. The three proposed criteria listed below should be adopted for unsolicited research project grant applications.

    Significance: The extent to which the project, if successfully carried out, will make an original and important contribution to biomedical and/or behavioral science.

    Approach: The extent to which the conceptual framework, design (including, as applicable, the selection of appropriate subject populations or animal models), methods, and analyses are properly developed, well-integrated, and appropriate to the aims of the project.

    Feasibility: The likelihood that the proposed work can be accomplished by the investigators, given their documented experience and expertise, past progress, preliminary data, requested and available resources, institutional commitment, and (if appropriate) documented access to special reagents or...

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