TOP 7 FROM F1000

Top 7 From F1000 Image by Tamily Weissman and Jean Livet / Harvard University 1. Mice have it licked » Imaging of many cortical neurons simultaneously in live mice maps crosstalk between specific neuron clusters, showing how brain circuits remodel while mice learn a task—in this case licking of water in response to different smells. T. Komiyama et al., Nature, 464:1182–86, 2010 Eval by Noam Ziv, Technion, Israel; Mark Mayford, Th

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1. Mice have it licked » Imaging of many cortical neurons simultaneously in live mice maps crosstalk between specific neuron clusters, showing how brain circuits remodel while mice learn a task—in this case licking of water in response to different smells.

T. Komiyama et al., Nature, 464:1182–86, 2010 Eval by Noam Ziv, Technion, Israel; Mark Mayford, The Scripps Research Inst.; Leonard Maler, Univ. of Ottawa ID: 3037957

2. Activating cell death » The long-awaited high-resolution crystal structure of the cell death–inducing apoptosome is a funnel made from four heterodimers that forces together and thus activates a pair of “cell executioner” caspase molecules.

S. Qi et al., Cell, 141:446-57, 2010. Eval by W. Douglas Fairlie and Peter Colman, Walter and Eliza Hall Inst.; Sharad Kumar, Centre for Cancer Biology, Australia; Hao Wu, Weill Medical College of Cornell Univ. ID: 3112956

3. The brain’s computer » A combination of calcium imaging and ...

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