WELLCOME LIBRARY, LONDON
1. Lighting up RNA
A novel technique for tagging and following RNA processes in live cells promises to illuminate RNA biology the way green fluorescent protein (GFP) did for the study of proteins. The tagging method consists of short RNA sequences that bind to GFP-like fluorophores and produce a wide range of colors. These RNA-fluorophore complexes can then be fused to RNAs in the cell.
J.S. Paige et al., “RNA mimics of green fluorescent protein,” Science, 333:642-46, 2011. Free F1000 Evaluation
2. G-coupled proteins unveiled Researchers used a series of techniques to reveal the structure of a G-protein coupled receptor, called the beta-2 adrenergic receptor-Gs protein complex, which belongs to a class of receptors that drives cellular responses to hormones and plays a role in ...
