IMAGE: WIKIMEDIA1. Virus amps up parasite disease
When the parasite that causes Leishmaniasis, a skin-ulcer disease transmitted by sandflies, is infected with a virus, it causes a more severe disease than when it is not infected, by triggering inflammatory cytokines in the host that paradoxically promote parasite's spread.
A. Ives et al., "Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis," Science, 331:775-78, 2011. Evaluated by Jan Rehwinkel and Caetano Reis e Sousa, Cancer Research UK; Breck Duerkop and Lora Hooper, U of Texas Southwestern Med Ctr; Heidi Snider and Abhay Satoskar, Ohio State Univ; Barbara Papadopoulou, Laval Univ, Canada; Jean-Luc Imler, Univ de Strasbourg, France; Christian Engwerda, Queensland Inst of Med Res, Australia. Free F1000 Evaluation
2. Cytokines, infection blockers Patients infected by Candida albicans -- the causative agent of chronic ...
