Transposons, mobile DNA elements found in the genomes of prokaryotic and eukaryotic organisms, move randomly from one site in a chromosome to another using a process catalyzed by transposases. This process, called transposition, occurs naturally but infrequently in cells as a means of genetic change. For many years scientists have used transposons for genetic research. A new system, combining Tn5 transposase and a Tn5-derived transposon to form a stable synaptic complex, forms the basis of EZ::
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The EZ::TN Transposon in vitro insertion kits eliminate the need for primer walking and subcloning of DNA when sequencing large plasmid and cosmid clones. The two-hour EZ::TN insertion reaction requires just 0.2 µg of plasmid or cosmid DNA to generate >106 independent sequencing templates. Each has a single randomly inserted transposon containing a selectable marker (Tetr or Kanr) and priming sites for sequencing. Individual transposon insertion ...
A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.
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In this webinar, Andre Mueller will introduce Aunty, the latest tool that scientists use for rapid, high-resolution protein stability testing.
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Today’s thermocyclers are more intuitive and flexible, letting scientists focus on their experiments rather than their instruments.
Long-lasting, bright F-actin staining made easy with Biotium's new ActinBrite™ High Affinity Phalloidin Conjugates.
The Aivia 15 release includes deep learning-powered tools for 2D and 3D cell segmentation.
The integrated solution enables parallel high-resolution analysis of hundreds to thousands of individual cells, addressing growing demand for scalable, multiomics approaches in single-cell research.
From confocal, widefield, and live cell imaging to multimode reading, the Agilent BioTek Cytation C10 confocal imaging reader delivers crisp, high-resolution images and the ability to image and analyze 3D samples.
