Malignant cells secrete vascular endothelial growth factor (VEGF) that then binds to specific receptors on endothelial cells to induce tumor angiogenesis. In September 15 Blood, Rizwan Masood and colleagues from Keck School of Medicine of the University of Southern California show that VEGF has an additional role in tumor development because it is also a direct growth factor for many tumor cells.Working on tumor cell lines in vitro, Masood et al. found that several tumor types (Kaposi's sarcomas
Malignant cells secrete vascular endothelial growth factor (VEGF) that then binds to specific receptors on endothelial cells to induce tumor angiogenesis. In September 15
Working on tumor cell lines
The finding that VEGF works directly on tumor cells that display its receptor may allow clinicians to predict whether using a VEGF inhibitor as part of the therapy ...
Add The Scientist as a preferred Google source to see more of our trusted coverage.
When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.
View this Issue
Explore strategies for improving recombinant adeno-associated virus production in transient HEK293 suspension cultures while maintaining vector quality and supporting scalable viral vector manufacturing.
Discover how tissue-resident memory T cells develop within the respiratory tract and how these findings are advancing respiratory virus immunity, vaccine research, and high-throughput immune profiling.
Bench architecture, primer design, and liquid handling set an assay's limit as throughput climbs.
Explore emerging mechanisms of immune checkpoint inhibitor resistance in hepatocellular carcinoma (HCC) and how combination immunotherapy strategies may improve antitumor immune responses and patient-specific treatment approaches.
European customers can now subscribe to Sino Biological’s newsletter to receive a special gift and unlock access to EliteScience benefits.
Sino Biological’s trial program enables qualified customers to evaluate SuperNuclease Pro in their specific bioprocessing applications, facilitating faster technology assessment and informed decision-making during process development
This release expands on Sino Biological's comprehensive Tau protein product portfolio, designed to accelerate neurodegenerative disease research.
Resipher measures cellular respiration (OCR) continuously in standard 96-well plates inside your incubator, for days to weeks. No media swaps, dyes, or transfers. A live-cell functional readout for drug safety, metabolism, and mitochondrial health.
