Courtesy of Roland Brosch
The regions absent from the attenuated vaccine strain Mycobacterium bovis BCG Pasteur relative to the M. tuberculosis H37Rv genome are shown as gray boxes. Open reading frames (ORFs) are represented as pointed boxes showing the direction of transcription, with colors reflecting the functional classification of the ORFs similar to the ones on the TubercuList server
Not long after the genome sequence of
Surprising many, Institut Pasteur scientist Roland Brosch and colleagues overturned a widely accepted theory about how M. tuberculosis had evolved.2 Skeletal deformities in ...