Vaping Damages Immune Cells, Researchers Find

A small, in vitro study concludes that e-cigarette vapor harms macrophages taken from human lung tissue.

Written byCatherine Offord
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The vapor inhaled from e-cigarettes is toxic to immune cells in the lung known as alveolar macrophages, according to an in vitro study published yesterday (August 13) in Thorax. Using lung tissue samples from eight nonsmokers, researchers at the University of Birmingham in the UK found that, over a period of 48 hours, the vapor led to the production of reactive oxygen species, the release of inflammatory cytokines, and the inhibition of phagocytosis in the cells—calling the perceived safety of the devices into question.

“I don’t believe e-cigarettes are more harmful than ordinary cigarettes,” study coauthor David Thickett says in a statement. “But we should have a cautious scepticism that they are as safe as we are being led to believe.”

Previous studies of e-cigarettes’ safety have focused on the liquid used in the devices before it is vaped. This study compared unvaped and vaped e-cigarette fluid and found that ...

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Meet the Author

  • After undergraduate research with spiders at the University of Oxford and graduate research with ants at Princeton University, Catherine left arthropods and academia to become a science journalist. She has worked in various guises at The Scientist since 2016. As Senior Editor, she wrote articles for the online and print publications, and edited the magazine’s Notebook, Careers, and Bio Business sections. She reports on subjects ranging from cellular and molecular biology to research misconduct and science policy. Find more of her work at her website.

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