Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.
Immunotherapy Treats Fibrosis in Mice
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
Immunotherapy Treats Fibrosis in Mice
Immunotherapy Treats Fibrosis in Mice

Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

lung
Illustration showing rod-shaped Mycobacterium tuberculosis bacteria in the lungs of a person with tuberculosis
Delayed T cell Response Allows Tuberculosis to Gain Foothold in Monkeys
Anna Napolitano | Jun 1, 2022
The results could help guide the design of new vaccines for the disease.
illustration of blue cancer cell extending tendrils around itself
Janus-Faced Neutrophils
Sophie Fessl | Mar 2, 2022
The immune cells facilitate healing, but they may also help tumors metastasize to the lungs after injury, a study in mice finds.
An illustrated schematic with a blue background describes how oxygenated perfluorocarbon can rescue respiratory failure in mammals.
Mammals Can Use Their Intestines to Breathe
Abby Olena | May 14, 2021
Researchers show that both mice and pigs are capable of oxygenating their blood via the colon—a capacity that, if shared by humans, could be leveraged in the clinic to minimize the need for mechanical ventilation.
Disturbed Microbes Contribute to Lung Damage from Oxygen Treatment
Ruth Williams | Aug 12, 2020
In humans, higher oxygen levels during ventilation are tied to an altered bacterial composition in the lungs, and mouse experiments show a causative link.
Autopsies Indicate Blood Clots Are Lethal in COVID-19
Ashley Yeager | Jul 10, 2020
A pathologist describes his observations from examining the bodies of those who succumbed to the coronavirus.
Could Statins Reduce the Severity of COVID-19?
Ashley Yeager | Jun 12, 2020
The cholesterol-lowering drugs quell inflammation and reverse endothelial tissue damage, hints that they might curb the body’s excessive immune response to SARS-CoV-2 infection.
ct scan lung covid-19 pneumonia coronavirus pandemic sars-cov-2 ground glass opacity
AI Learns from Lung CT Scans to Diagnose COVID-19
Claire Jarvis | Jun 10, 2020
Lesions in the lungs of patients with pneumonia caused by a SARS-CoV-2 infection are distinct from those caused by bacteria.
Image of the Day: Defective Cilia
Amy Schleunes | Apr 7, 2020
Super-resolution imaging identifies abnormalities in the hair-like protrusions on a cell’s surface and may help facilitate earlier detection of primary ciliary dyskinesia.
Blood Pressure Meds Point the Way to Possible COVID-19 Treatment
Ashley Yeager | Apr 2, 2020
There is little evidence that antihypertensive drugs worsen COVID-19, and scientists are instead exploring the idea that such medications—or their downstream effects—may actually alleviate symptoms.
Cracking Down on Cancer: A Profile of Owen Witte
Diana Kwon | Apr 1, 2020
Through his studies on cancer-causing viruses, the University of California, Los Angeles, professor has helped develop lifesaving treatments.
Image of the Day: Bubble Suckers
Amy Schleunes | Feb 28, 2020
Unable to break through the water’s surface, tadpoles have a unique workaround for breathing air.
Vapers Reported Adverse Health Effects Online for Years: Study
Ashley Yeager | Jan 7, 2020
Researchers mined an electronic cigarette users’ online discussion forum and found reports of headaches, coughing, itching, and throat pain.
Keto Diet Protects Mice from Flu
Abby Olena | Nov 15, 2019
The low-carb, high-fat diet increases the presence of gamma-delta T cells in the animals’ lungs, improving a mucus barrier against the virus.
young man vaping
Scientists Study Vaping’s Harm as Second Death Reported
Nicoletta Lanese | Sep 5, 2019
In light of recent reports of electronic-cigarette–related illness and death, UNC Chapel Hill professor Robert Tarran discusses the dangerous effects of e-liquids on the lungs.
firefighters emergency responders 9/11 world trade center terrorist attacks september 11, 2001 obstructive airway disease pulmonary function lung health metabolites diet omega-3 fatty acids
Metabolites May Predict Lung Injury in 9/11 First Responders
Emma Yasinski | Sep 3, 2019
Firefighters who didn’t develop obstructive airway disease after the World Trade Center attacks had higher levels of omega-3 fatty acids and other factors that hint at possible protective effects of diet.
Researchers Discover New Family of Viruses
Catherine Offord | Sep 1, 2019
The redondoviruses, named for their circular DNA, inhabit the human respiratory tract and may be linked to disease.
Mouse club cells
Image of the Day: Resilient Lung Cells
Nicoletta Lanese | Aug 1, 2019
A specific type of lung cell withstands flu infection by doubling down on DNA repair.
Even Healthy Tissues Carry Clusters of Cells with Mutations: Study
Ashley Yeager | Jun 7, 2019
Most of the genetic alterations are harmless, but some may contribute to cancer.
CRISPR mice lungs gene genetic editing disease womb fetus
Mice Gene-Edited While Still in the Womb
Chia-Yi Hou | Apr 19, 2019
CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.