Skip to main content

XMRV doesn't cause chronic fatigue

Two studies point to contamination of patient samples as the cause of a controversial 2009 finding that linked the mouse virus XMRV with chronic fatigue syndrome.

Written byTia Ghose
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00

Microscope image of XMRV (Xenotropic murine leukemia virus - related virus)WIKIMEDIA COMMONS, CENTER FOR DISEASE CONTROL AND PREVENTION

Two studies have cast further doubt on a 2009 report that a mouse virus is linked to chronic fatigue syndrome. The studies, both published Tuesday (May 31) in Science, point to lab contamination as the source of xenotropic murine leukemia virus-related virus, or XMRV, in cell samples from chronic fatigue patients.

As a result of these findings, both the scientific community and chronic fatigue patients "will ultimately have to accept the scientific proof that there's just no hint of a connection to that disease," Stephen Goff, a virologist at the Columbia University Medical Center in New York who was not involved in the study, told The Scientist.

Mikovits' 2009 paper reported that 67 percent of CFS patients, but only 10 percent of healthy controls, tested ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

Related Topics

Related articles background image
August 2026 Digest cover
August 2026

Epic Fail: Sea-Monkeys Sabotage Fieldwork

When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.

View this Issue
Improving rAAV Production for Viral Vector Manufacturing

Improving rAAV Production for Viral Vector Manufacturing

cytiva logo
Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
Scientist holding a clear 384-well PCR microplate in a laboratory

What Dictates PCR Success Before Amplification Begins?

Integra Logo
Overcoming Immunotherapy Resistance in Liver Cancer

Overcoming Immunotherapy Resistance in Liver Cancer

Axion Biosystems

Products

Sino Biological Logo

Sino Biological Launches European Newsletter Campaign with Exclusive Welcome Gifts

Sino Biological Logo

Sino Biological Launches SuperNuclease ® Pro with Free Trial Program

Sino Biological Logo

Sino Biological Launches Precisely Characterized Full-Length p-Tau217 Protein to Advance Next-Generation Alzheimer’s Biomarker Assay Development

A photo of a scientist placing the Resipher device on a 96-well plate.

Resipher: Continuous Live-Cell Mitochondrial Respiration Monitoring in 96-Well Plates

Lucid Scientific logo