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Not all degenerated intervertebral discs are painful; a new study identified a subset of disc cells that triggers a pathway to pain.

CRISPR-Cas9 editing leads to widespread loss of the targeted chromosome in human T cells, but scientists recently discovered a way to prevent such loss.

A protein’s timely appearance is crucial for Toxoplasma gondii’s unique replication cycle.

A CRISPR-based screening platform helped scientists identify a transcription factor that makes CAR T cells better at killing cancer cells. 

Researchers developed a “test tube” so tiny that it can hold a single cell. These vials enabled them to connect protein secretion levels with surface markers and transcriptome data from the same cell. 

A 3D variation of pooled CRISPR screens could connect the dots between autism spectrum disorder genetics and cell fate pathways in the developing brain.

Simulated microgravity in mice reveals a constellation of genes that may influence muscle weakening during spaceflight.

Dietary changes rapidly alter T cell metabolism, but the effects can be reversed.

CD4 T cells mediate gut symptoms that indicate early Parkinson’s disease.

Dorothy Shippen and Borja Barbero Barcenilla investigated how spaceflight affects telomeres of Arabidopsis seedlings grown on the International Space Station.

Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 

Forgetting things appears to be a productive process and not a passive loss of information.