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A new research centre is being established in Singapore that will use a multidisciplinary approach to study systems biology.

has called for an international moratorium on human reproductive cloning.

The Bcl-2 protein family members Bax and Bak play an important role in regulating apoptosis.1,2 But following their discovery in the 1990s, they did not take center stage because researchers didn't anticipate their role as "critical effectors of programmed cell death," says Craig Thompson, scientific director of the Abramson Family Cancer Research Institute at the University of Pennsylvania. But the limelight is now upon them as Thompson and his colleagues at the Abramson Institute, in collabora

Editor's Note: This is the second of two articles that looks at the progression of AIDS research over the 20 years since its identification. The first part: M.E. Watanabe, "AIDS, 20 years later," The Scientist, 15[12]:1, June 11, 2001. Despite billions of dollars spent in research funds and a brief reprieve in Western nations after the introduction of multidrug therapy, AIDS continues to win its battle against humankind. First diagnosed 20 years ago, there are still no cures and no vaccines. Pre

Click here for additional photos of life scientists elected to the National Academy of Sciences This past May, the National Academy of Sciences (NAS) elected its new members and with the election came another round of criticisms that the NAS is elitist and gender biased, that the election process is outmoded, and that truly great scientists go unrecognized.1 Allegations aside, however, this year's election was the biggest ever--the first in which 72 members were chosen--and it signals the recog

"In the case of the Controlled Substances Act, the statute reflects a determination that marijuana has no medical benefits worthy of an exception (outside the confines of a government-approved research project)." -Justice Clarence Thomas1 The Supreme Court's recent ruling against manufacturing and distributing medicinal cannabis does not appear to have had any immediate impact on either basic or clinical research studies under way. Some investigators, however, remain leery about the potential f

To commemorate the 20th anniversary of the discovery of AIDS, the National Institutes of Health announced on June 4 the launch of a new Web site chronicling the history of AIDS research. "In Their Own Words: NIH Researchers Recall the Early Years of AIDS" (http:// aidshistory.nih.gov) highlights five main periods in AIDS research: initial encounters with the disease, the AIDS epidemic, early research efforts, the discovery of HIV, and the search for effective treatments. Each section includes a

A power shutdown last month at the University of California, San Francisco, sent physiology professor Mary F. Dallman into a panic. Her lab studies the effects of stress on the pituitary-adrenal axis in rats' brains, and one of her postdocs had recently begun the sort of 20-day, $10,000 experiment typically conducted by her lab. The pituitary-adrenal axis "is highly circadianly driven," Dallman explains, "and when the lights go out in the middle of the day, you're giving the circadian clock a

An alternative analysis of the human genome sequence information refutes the assertion that genes have been transferred directly from bacteria to man.

A book about the mysteries of the World's Oceans scoops science's most prestigious literary award.

On June 5, 1981, a one-and-a-half page paper in Morbidity and Mortality Weekly Report (MMWR) noted cases of Pneumocystis carinii pneumonia in five gay men in Los Angeles. The men also suffered from cytomegalovirus (CMV) infections and candidal infections of the mucosa,1 and they used recreational inhalant drugs. The editorial note pointed out: "Pneumocystis pneumonia in the United States is almost exclusively limited to severely immunosuppressed patients." "I was sitting in my office in Buildi

Research in pharmacogenomics points to a seismic shift in drug therapy, from a "one-size-fits-all" approach to a new era of personalized medicine, in which doctors will increasingly be able to prescribe the right drug at the right dose for the right person. Often used interchangeably with pharmacogenetics, pharmacogenomics is the study of how inherited genetic differences in humans influence individual responses to drugs. Courtesy of Genaissance PharmaceuticlsGerald F. Vovis Although a new worl