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These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.A. O'Doherty et al., "An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes," Science, 309:2033–7, Sept. 23, 2005.This is the first study to show that a human chromosome can be introduced into a mouse's germline and transmitted to successive generations. The authors introduced a copy of human chromosome 21. The mice

Dope may help the growth of new brain cells.

Take the bully out of the schoolyard and another quickly takes his place.

An interdisciplinary team at Rensselaer Polytechnic Institute (RPI) in Troy, NY, has developed a computer program that uses protein structural information to predict how proteins separate on a chromatography column.1 "This is something that is usually done by trial and error, but in this case we've used information from the experiment to build a computer model that enables us to make that prediction," explains coauthor Curt Breneman, a computational chemist at RPI.The technique first takes exper

Foot soldiers in the "Omics revolution" have an ally in the BioOdyssey Calligrapher MiniArrayer, a new entry into the benchtop microarray printing arena from Bio-Rad Laboratories.

they have been a boon to scientists.

Researchers imaging DNA gels can put away their UV-protective gear.

has just released the G:BOX, a modular image analysis system designed for a range of applications and budgets.

Anyone can buy naming rights to a star, but Gary and Linda Dower are hoping to pick up their very own observatory.

Scientists fear new EU science ethics board is too conservative, inexperienced

Measure would have ended government funding for researchers using Class B dealers

Scientists and journals say fired MIT researcher's misconduct raises concerns about multiple papers