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Foundations | Discovery of the First Angiogenic Factor Courtesy of Judah Folkman During the mid-1970s to early 1980s, my laboratory was trying to isolate an angiogenic stimulator from tumors, the factor we called TAF [tumor angiogenic factor] in our notebooks. This was at a time when no angiogenic stimulators were known to exist, nor had any angiogenesis inhibitors been discovered. In fact, few, if any, colleagues believed that angiogenic proteins would ever be found. "We used tumors grow

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