AI Controls Laser-Guided Robot Worms

Automated control of light-responsive nematode worms marks the first foray into the development of multicellular, biorobotic organisms.

Written byRuth Williams
| 3 min read
An illustration of a microscope objecting beaming blue light onto a nematode worm with the labels objective, agar substrate, micro laser beams, paralyzed c. elegans, and controlled c. elegans movement

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ABOVE: Set up of the laser-guided RoboWorm system
REPRINTED WITH PERMISSION FROM X. DONG ET AL., SCIENCE ROBOTICS, 6:EABE3950, 2021

Roboticists have for the first time built an automated computational system for controlling the movements of a living multicellular organism—a genetically engineered worm (Caenorhabditis elegans) whose muscles contract in response to blue light. The laser-guided nematode, described last week (June 30) in Science Robotics, is called RoboWorm.

“Most of the biohybrid microrobots [in development] are mainly based on bacteria,” says Li Zhang, a nanomaterials and microrobotics researcher at the Chinese University of Hong Kong who was not involved in the research. But in this study, “they propose the use of C. elegans, a worm, as a robotic agent . . . [in a] very interesting and smart way.”

The natural world is an endless source of inspiration for human feats of engineering, and nowhere is that more apparent than in the ...

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  • ruth williams

    Ruth is a freelance journalist. Before freelancing, Ruth was a news editor for the Journal of Cell Biology in New York and an assistant editor for Nature Reviews Neuroscience in London. Prior to that, she was a bona fide pipette-wielding, test tube–shaking, lab coat–shirking research scientist. She has a PhD in genetics from King’s College London, and was a postdoc in stem cell biology at Imperial College London. Today she lives and writes in Connecticut.

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