An Early Start: The Impact of the Microbiome on Pediatric Development in the First Year of Life

A better understanding of early childhood microbiome shifts offers a unique window for detecting disease risk and intervening appropriately.


Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

Dirk Gevers, Ph.D., Global Head, Microbiome Solutions, World Without Disease Accelerator
Richard Insel, M.D, Global Head, Healthy Baby Initiative, World Without Disease Accelerator

The incidence and prevalence of pediatric immunity-related conditions—from food allergy to type 1 diabetes—has increased over recent decades.1-3 Researchers, clinicians, and policymakers are trying to identify potential underlying causes for this phenomenon to prevent and intercept these diseases. In particular, the World Without Disease Accelerator (WWDA), an R&D group within Janssen Research and Development, LLC, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, is pursuing science related to the infant gut microbiota, which is thought to play a key role in the development of pediatric allergic and autoimmune diseases.

Starting with a Single Step

The infant microbiome is shaped by external factors that begin in utero.4 These factors include mode of delivery, maternal and pediatric diet composition (e.g., breast milk vs. cow’s milk formula) and ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

iStock

Agilent BioTek Cytation C10 Confocal Imaging Reader

agilent technologies logo