Researchers identify signatures that predict how a person will respond to an immune system stimulus.

Combining spatial context with multiplexing depth for cell characterization

Stronger interferon production, greater T cell activation, and increased susceptibility to autoimmunity are just some of the ways that females seem to differ from males.

The Johns Hopkins University researcher bucked the prevailing idea that the body would not launch an immune response against its own tissues, and in doing so established an entirely new scientific discipline.

A handful of viruses have been associated with long-term, debilitating symptoms in a subset of those who become infected. Early signs hint that SARS-CoV-2 may do the same.

The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.

Many dominant T cell variants decline during pregnancy and reappear afterward, possibly explaining why relapses of the autoimmune disease are less common when women are expecting.

A Chicago-based center that has long operated a clinical trial program for stem cell therapies, has stopped recruiting further patients as its chief, Richard Burt, leaves for a research sabbatical.

Neutrophil extracellular traps may hold clues to the cause of skin lesions in patients with a painful condition called hidradenitis suppurativa.

Molecules produced by resident bacteria and their hosts may signal immune cells to attack the body’s own tissues.

Antigens originating from the microbiome may trigger an autoimmune response.

The second phase of the Human Microbiome Project reports on microbial composition in prediabetes, inflammatory bowel disease, and pregnancy.

T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.

Researchers find that it’s not just high-risk genes, but how children’s bodies respond to their own intestinal microbiota that relates to future diagnoses of type 1 diabetes.

Results from an observational study find that the introduction of a routine vaccine in Australia coincided with a fall in the incidence of the autoimmune condition.

The results suggest the virus could severely alter brain development in infants infected after birth, but blocking a signaling protein early on might ease certain symptoms.

Patients with the rare autoimmune condition, highlighted in the Oscar-nominated film The Big Sick, currently have limited treatment options.

Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.

A small clinical trial demonstrates that peptide immunotherapy can halt the progression of early-stage type 1 diabetes.