autoimmune disease
Mouse Pups Infected With Zika Show Symptoms Into Adulthood
Mouse Pups Infected With Zika Show Symptoms Into Adulthood
Ashley Yeager | Jun 6, 2018
The results suggest the virus could severely alter brain development in infants infected after birth, but blocking a signaling protein early on might ease certain symptoms.
Drug for Still’s Disease Shows Promise in Phase 2 Trial
Drug for Still’s Disease Shows Promise in Phase 2 Trial
Shawna Williams | Mar 1, 2018
Patients with the rare autoimmune condition, highlighted in the Oscar-nominated film The Big Sick, currently have limited treatment options.
Immune Checkpoint Found Lacking in Type 1 Diabetes
Immune Checkpoint Found Lacking in Type 1 Diabetes
Ruth Williams | Nov 15, 2017
Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.
Immunotherapy Promising for Diabetes: Study
Immunotherapy Promising for Diabetes: Study
Aggie Mika | Aug 9, 2017
A small clinical trial demonstrates that peptide immunotherapy can halt the progression of early-stage type 1 diabetes.
The Celiac Surge
The Celiac Surge
Catherine Offord | Jun 1, 2017
A rapid increase in the global incidence of the condition has researchers scrambling to understand the causes of the trend, and cope with the consequences.
Infographic: Immune Irritation in the Gut
Infographic: Immune Irritation in the Gut
Catherine Offord | May 31, 2017
A look at how gluten affects patients with celiac disease
Image of the Day: Seizure-Inducing Worms
Image of the Day: Seizure-Inducing Worms
The Scientist Staff | Feb 15, 2017
Onchocerca volvulus, a parasitic worm, may cause a fatal form of epilepsy in children by inducing an autoimmune reaction.
Lisa Boyette Started a Nonprofit to Save Her Brother and Cure Other Diseases
Lisa Boyette Started a Nonprofit to Save Her Brother and Cure Other Diseases
Alison F. Takemura | Oct 1, 2016
Founder and CEO, Curable; Adjunct Assistant Professor, University of Pittsburgh. Age: 35
Saving Jon
Saving Jon
The Scientist Staff | Sep 30, 2016
Meet the researcher/entrepreneur who started a nonprofit that seeks to solve the science behind a rare disease that threatens the life of her younger brother.
Antibiotic Therapy During Infancy Increases Type 1 Diabetes Risk in Mice
Antibiotic Therapy During Infancy Increases Type 1 Diabetes Risk in Mice
Alison F. Takemura | Aug 22, 2016
Three therapeutic doses administered during early life disturb the animals’ microbiomes and lead to enduring changes in the immune systems of non-obese diabetic mice, researchers report.