Ribbon diagram of the protein coat of an adeno-associated virus
Preprints Propose Constellation of Causes for Kids’ Liver Disease
Two independent groups suggest the suite of recent unexplained hepatitis cases may stem from coinfection with an adeno-associated virus and a helper adeno- or herpesvirus, a duo which may be especially virulent in children with a particular genetic variant.
Preprints Propose Constellation of Causes for Kids’ Liver Disease
Preprints Propose Constellation of Causes for Kids’ Liver Disease

Two independent groups suggest the suite of recent unexplained hepatitis cases may stem from coinfection with an adeno-associated virus and a helper adeno- or herpesvirus, a duo which may be especially virulent in children with a particular genetic variant.

Two independent groups suggest the suite of recent unexplained hepatitis cases may stem from coinfection with an adeno-associated virus and a helper adeno- or herpesvirus, a duo which may be especially virulent in children with a particular genetic variant.

pediatrics
Liver glowing red underneath human torso
Mysterious Hepatitis Cases Reported in Young Children
Natalia Mesa | Apr 18, 2022
Officials have ruled out known hepatitis viruses as the cause of a rash of illnesses in Europe and the US.
A black line drawing of a mother putting a face mask on a child with a white background
SARS-CoV-2 Antigens Leaking from Gut to Blood Might Trigger MIS-C
Alejandra Manjarrez | Jun 3, 2021
Researchers find traces of SARS-CoV-2 in the stool and blood of kids with the post–COVID-19 inflammatory disorder, and signs of increased intestinal permeability.
Antibodies in breastmilk from SARS-CoV-2 infection or mRNA vaccination neutralize the virus.
Antibodies Against SARS-CoV-2 in Breast Milk Differ Between Vaccinated and Infected Mothers
Roni Dengler, PhD
All antibodies against SARS-CoV-2 found in breast milk neutralized the virus.
A hospital corridor with empty gurney
Severe Symptoms of MIS-C Typically Clear Within Six Months: Study
Catherine Offord | May 26, 2021
Some children who experience the severe inflammatory condition after COVID-19 may continue to experience milder problems such as muscle weakness or anxiety even after that period, according to a small observational study in the UK.
kidney acute kidney injury covid-19 mis-c children kids nephrology long covid pandemic coronavirus sars-cov-2
Some Children with COVID-19 or MIS-C Face Kidney Injury: Study
Marcus A. Banks | Mar 10, 2021
The link between SARS-CoV-2 and potential stress to kidneys is unclear, but damage to the organs has been documented in adults with COVID-19 too.
a child in a hospital bed
Kids’ Severe COVID-19 Reaction Bears Unique Immune Signature
Shawna Williams | Sep 29, 2020
The rare complication known as multisystem inflammatory syndrome in children (MIS-C) differs from both Kawasaki disease and severe adult cases of COVID-19, a study finds.
COVID-19 Is “Very Different” in Young Kids Versus Adults
Abby Olena | Jun 16, 2020
A study of 34 children hospitalized with a coronavirus infection in China reveals that fever and coughing were common, but the type of lesions typically seen in the lungs of adults with COVID-19 were rare.
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Carolyn Wilke | Apr 1, 2019
Computational biologist Jinghui Zhang of St. Jude realized scientists could work more efficiently with tools and genomic data shared on the cloud.
New York Faces Worst Measles Outbreak in Decades
Catherine Offord | Jan 10, 2019
In one county alone, more than 100 cases have been confirmed since October.
Genome, Exome, RNA Sequencing Applied to Pediatric Cancer Cases
Ashley Yeager | Oct 18, 2018
Combining data from the genetic testing techniques can guide patient care, scientists say.
JAMA Journals Retract Six Papers by Cornell Researcher
Ashley Yeager | Sep 19, 2018
Problems with Brian Wansink’s research articles surfaced in 2017 and have now resulted in 13 retractions total.
Fresh Concerns Raised About UIC Researcher’s Pediatric Drug Study
Catherine Offord | Jul 3, 2018
New documents reveal that Mani Pavuluri had enrolled her sons as controls in a prematurely halted drug trial, a ProPublica investigation finds.
This Flu Season Killed 172 Kids
Sukanya Charuchandra | Jun 11, 2018
Vaccination reduced the risk of death by two-thirds for children with no other health problems.  
In Utero Transplant in First Clinical Trial Successful
Jim Daley | May 30, 2018
Doctors treated the fetus, who has alpha thalassemia major, with cells from her mother’s bone marrow.
Prevalent Form of Childhood Leukemia May Be Preventable
Sukanya Charuchandra | May 22, 2018
Early exposure to common microbes could stop leukemia from manifesting in children.
Researchers Turn to Implantable Robots to Regenerate Tissue
Shawna Williams | May 1, 2018
The devices, which could one day treat children with esophageal atresia and short bowel, were recently tested in pigs.
Doctors Successfully Treat Rare Genetic Disorder in Utero
Jim Daley | Apr 26, 2018
The disorder, called X-linked hypohidrotic ectodermal dysplasia, leaves patients unable to produce sweat, which can be life-threatening.
Researchers Publish First Pan-Cancer Genomic Analyses in Pediatric Patients
Catherine Offord | Feb 28, 2018
Two large-scale studies reveal new insights into the genomic characteristics of childhood cancers.
Opinion: Share Your Data
Cameron Craddock, Arno Klein, and Michael P. Milham | Oct 24, 2017
Our analysis of a collection of open-access datasets quantifies their benefit to the scientific community.