Severe Symptoms of MIS-C Typically Clear Within Six Months: Study

Some children who experience the severe inflammatory condition after COVID-19 may continue to experience milder problems such as muscle weakness or anxiety even after that period, according to a small observational study in the UK.

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The majority of children hospitalized with multisystem inflammatory syndrome—a rare but serious condition associated with SARS-CoV-2 infection—appear to overcome their most severe symptoms within six months, according to a small observational study published on Monday (May 24) in The Lancet Child and Adolescent Health. The research, which followed 46 young people admitted to Great Ormond Street Hospital (GOSH) in London between April and September, found that some of them continued to have milder problems such as muscle weakness and emotional difficulties even after that six-month period.

“These findings can hopefully signal cautious optimism that many of the most severe effects . . . appear to resolve within six months,” study coauthor Justin Penner of GOSH says in a statement. “However, the persisting fatigue, difficulty exercising, and mental health effects we saw in some children, which can interfere with daily lives, must be closely monitored, and patients ...

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