Pseudomonas

Size-sensing mechanism in animal cells could determine cell cycle length to control growth

Reports based on D-type cyclin knockouts show cell cycle is not cyclin dependent

Researchers report in two separate papers in Science this week on novel methods used by bacteria to avoid being killed by antibiotics. In one study, scientists at the Rockefeller University report that the bacterial cells known as persisters, which tolerate but do not become resistant to antibiotics, preexist in a population and that their random switching between normal and slow-growing persister states enables them to escape antibiotic killing. And in an accompanying paper, Stanford University

Looking to improve the quality of tools for discovering genomic regulatory regions, researchers at the National Institutes of Health combined Chromatin immunoprecipitation (ChIP) of hyper-acetylated histones, with serial analysis of gene expression (SAGE) technology. The process that they call genome-wide mapping technique (GMAT) could provide an alternative to ChIP-on-a-Chip techniques.1Developers and others call it unbiased and quantitatively better. "They sequence everything they bring down,

claims prognostic use for microarray in CLLs, but others doubt findings

Data supports model for looping mechanism governing long-distance interactions

Statistical analysis reveals evidence for molecular clock in neutral DNA substitutions

Isothermal amplification kits of lyophilized reagents for field use could appear soon

Study explores how host-parasite interactions select for genome number

Lamprey study shows distinct mechanisms of lymphocyte receptor diversity among vertebrates

could be used for sex selection