ian le guillou

Ian Le Guillou

Ian is a freelance journalist based in Paris, covering health and biomedical research. After hanging up his lab coat in 2012, Ian worked for several years in communications for medical research charities in the UK before going freelance.

Articles by Ian Le Guillou
bace1 alzheimer's disease gga3 axon neuron
Alzheimer’s-Linked Mutation Causes Blockages in Neurons
Ian Le Guillou | Nov 20, 2020 | 3 min read
The variant causes a buildup of BACE1 protein in axons in cultured neurons and mice. Researchers say it might be time to rethink failed trials that inhibit BACE1 to treat the neurodegenerative disease.
tau pet scan tracer tauopathy alzheimer's disease progressive supranuclear palsy corticobasal degeneration pick's disease frontotemporal lobal degeneration ftd alzheimer's disease neurodegeneration
New Tracer Gives Clear Picture of Alzheimer’s and Other Dementias
Ian Le Guillou | Oct 29, 2020 | 3 min read
An imaging agent reveals aggregated tau protein in the brain during PET scans and could improve the diagnosis of neurodegenerative diseases, particularly tauopathies.
amyloid-beta amyloid plaque alzheimer's disease coarse-grained neurodegeneration ab40 ab42
Newly Found Alzheimer’s Plaque Type Linked to Early-Onset Disease
Ian Le Guillou | Sep 28, 2020 | 4 min read
These “coarse-grained” plaques resemble those that clog up the brain’s blood vessels in a different disease, pointing to links between the vascular system and the neurodegenerative disease.