Credit: © SHARON MORRIS" /> Credit: © SHARON MORRIS In the 1940s Jules Freund, inventor of Freund's adjuvant, worked on developing antibodies in horse to rabbit serum globulin. In a 1947 Journal of Experimental Medicine study, Freund describes the horses by number: 1026, 999, 1127. To others, they had names like Sylvester, Moses, and Doc Fried. The horses had retired from the New York City police department to reside at stables on a 170-acre plot of land in the tiny tow

Growing a New Antidepressant Nine years ago, Rusty Gage shattered a neuroscience dogma when he showed human brains give birth to new neurons. Today, a company is eager to take those findings to the clinic.By Kerry Grens ARTICLE EXTRAS 1 and Liz Gould and Bruce McEwen at Rockefeller had published a suite of studies on the effects of stress on neurogenesis in rodents.2 But the field was sparkling wi

A HARSH DECREE Everything may die, nothing may be regenerated ARTICLE EXTRAS1 "I think it really was a turning point in the acceptance of the phenomenon as being real," Gould says. In the late 1990s Gould observed neurogenesis in the adult tree shrew as well,2 but the question remained: Did it occur in humans? "For us to believe it's more than an epiphenomenon, we needed to see if it occurs in humans," Gage s

Continuing a debate that started several months ago, The Lancet this month published several letters criticizing the European Journal of Cancer's decision to quietly withdraw a publication about mammography from its Web site without any explanation. 

Earlier this weak a judge dismissed a linkurl:lawsuit;http://www.the-scientist.com/news/display/52935/ filed by primate researcher Sally Boysen against Ohio State University (OSU). Boysen claims the University shut down the Chimpanzee Cognition Center at OSU and moved the animals to a sub-standard facility without her approval. Boysen also holds the university responsible for the death of two animals that died after their relocation. OSU says the Center was closed and the animals moved because B

I am waiting for a hypoallergenic cat. Not one to keep, but just one to prove all the skeptics wrong. In the January issue of the The Scientist I wrote an linkurl:article;http://www.the-scientist.com/article/display/39383/ about what scientists think of Allerca's hypoallergenic cats. The California company claims to have found and bred the world's first scientifically proven hypoallergenic cat, but most of the scientists I spoke with are dubious of its claims, not to mention the founder has a bi

Artists dive inside the body to expose its secret elements

Decision will determine whether a scientist can seek damages from Ohio State University over chimp deaths

The paper: J.D. Fontenot et al., "Regulatory T cell lineage specification by the forkhead transcription factor Foxp3," Immunity, 22:329-41, 2005. (Cited in 217 papers) The finding: Using a GFP-tagged knockin mouse, Alexander Rudensky's group at the University of Washington in Seattle showed that the expression of the transcription factor Foxp3 defines a subset of regulatory T cells involved in suppressing autoimmune activity. The

Credit: © 2007 PAOLO CAPPELLI" /> Credit: © 2007 PAOLO CAPPELLI On weekends, Fabrizio Chiti can be found behind the wheel of his RV, exploring the Italian countryside with his wife and daughter. A decade ago, as an undergraduate at the University of Florence, Chiti never imagined he would be doing science in his home country, let alone in the same department where he became fascinated by proteins. "I was told there were no chances for me," Chiti says. "The opportunities and funding f

Credit: courtesy of world Almanac library" /> Credit: courtesy of world Almanac library Somewhere between "Bracelet Showcase" and "Now You're Cooking" biologist Ferid Murad made his QVC television debut on January 21, 2007. The winner of the 1998 Nobel Prize in Medicine or Physiology graced the studios of one of the largest American home shopping television networks to hawk his new book, The Wellness Solution, penned with QVC's own Medical Wellness Doctor Edward Taub. Taub's regular

A University of Missouri probe of a Science paper exonerates the lead author and two co-authors, but a fourth author is on the lam, and still under scrutiny