binding protein aP2 protects transgenic mice deficient in apolipoprotein E against atherosclerosis.

Antigen-specific T cell-mediated gene therapy can inhibit the development of collagen-induced arthritis, a murine model of rheumatoid arthritis.

LFA703, a statin with high binding affinity for the LFA-1 site but low activity against HMG-CoA reductase has increased anti-inflammatory effects.

Continuous force or shear stress from fast flowing fluid must be applied on adherent white blood cells to facilitate migration across endothelium.

the process behind increasing antibody affinities after multiple exposures to the same antigen.

Retinoid hormones can induce post-maturation apoptosis through the Apo-2L/TRAIL death ligand.

The establishment of a new research centre for complementary medicine at Harvard Medical School signals a growing interest in subjecting complementary therapies to scientific scrutiny.

Staphylococcus aureus.

Blood and urine biomarkers of renal dysfunction and DNA damage can be used to detect environmental exposure to pollutants and measure their biological effect before overt disease develops.

Endothelial cell dysfunction may contribute to the progress of multiple sclerosis (MS) but directly measuring the extent of damage to this layer of cells has been difficult. In May Neurology, Alireza Minagar and colleagues from the University of Miami report that the level of endothelial cells release microparticles (EMP) expressing CD31 in the blood is a potential marker for endothelial damage and progression of MS.Minagar et al developed a flow cytometric assay and measured levels of two class

Identification of viral DNA in the myocardium of paediatric transplant recipients is predictive of adverse clinical events, including coronary vasculopathy.

An independent genetic factor, the mannose binding lectin gene influences liver disease severity in cystic fibrosis patients.