Self-replicative RNA vaccines are capable of protecting mice against influenza A, respiratory syncytial virus (RSV), and a tick-borne encephalitis virus.

Evidence exists that bone marrow cells can transform into skeletal muscle and brain tissue. In the 4 May Cell Diane Krause and colleagues at Yale University School of Medicine, New Haven have for the first time identified a haematopoietic stem cell in mice that can transform into virtually any cell type.Krause et al transplanted bone marrow haematopoietic stem cells from adult male mice into irradiated female mice, and then tested for the presence of Y chromosomes in various tissue specimens fro

The poisonous gas CO may serve as a novel inhalation therapy able to reduce the consequences of acute lung injury.

Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory responses.

mediated response and protective immunity in mice.

associated LIM gene destabilizes actin anchorage sites in cardiac muscle.

Women with unexplained infertility might have a genetic susceptibility to failure of embryo implantation due to small MUC 1 allele size.

Immunological adjuvants may improve survival of activated T cells via induction of the Bcl-3 gene.

Despite intense speculation about a possible link between the rates of administration of the MMR vaccine and an increase in the incidence of autism, the underlying biochemical mechanisms of the condition remain unknown. In May Annals of Neurology Karin Nelson and colleagues from the National Institute of Neurological Diseases and Stroke, Bethesda, US show that children with autism have an increase in certain neuropeptides and neurotrophins in their peripheral blood from the first days of life.Ne

ve T cell precursors to efficient cytotoxic cells can occur only after a single brief antigen exposure in the absence of 'helper' T cells.

A combination of cytology and methylation markers in breast-duct fluid could be useful for detecting breast cancers that are missed by mammograms.

High serum concentrations of the alpha chain IL-2 receptor are highly correlated with a shorter survival of patients diagnosed with head and neck squamous-cell carcinoma.