Biologists Create New Maps of Caenorhabditis elegans Neurons

The connectomes trace 385 neurons in the male worm and 302 neurons in the hermaphrodite worm.

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Biologists have mapped out the neural connections between each neuron and with organs in the worm Caenorhabditis elegans, in a study published in Nature on July 3. The connectomes trace 385 neurons in the male worm and 302 neurons in the hermaphrodite worm.

“It’s a major step toward understanding how neurons interact with each other to give rise to different behaviors,” says coauthor Scott Emmons, a developmental biologist at the Albert Einstein College of Medicine in New York, to The New York Times.

Previous research by Sydney Brenner’s group at the Salk Institute in the 1970s mapped the connectome of the hermaphrodite sex of C. elegans, but it was incomplete. “We just had fragments of the worm’s wiring,” says Emmons. This study adds the male connectome and provides more complete connections for both sexes. “The new connectomes provide much more comprehensive information than the old data sets ...

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